Mucous membrane pemphigoid

G Du, S Patzelt, N van Beek, E Schmidt - Autoimmunity Reviews, 2022 - Elsevier
Mucous membrane pemphigoid (MMP) is a clinically and immunopathologically
heterogenous disease with an incidence of about 2/million inhabitants/year in central …

[HTML][HTML] Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring

SD Ahadome, DJ Abraham, S Rayapureddi, VP Saw… - JCI insight, 2016 - ncbi.nlm.nih.gov
Mucous membrane pemphigoid (MMP) is a systemic mucosal scarring disease, commonly
causing blindness, for which there is no antifibrotic therapy. Aldehyde dehydrogenase family …

[HTML][HTML] Bullous Autoimmune Dermatoses: Clinical Features, Diagnostic Evaluation, and Treatment Options

N van Beek, D Zillikens, E Schmidt - Deutsches Ärzteblatt …, 2021 - ncbi.nlm.nih.gov
Background Bullous autoimmune dermatoses are a clinically and immunopathologically
heterogeneous group of diseases, characterized clinically by blisters or erosions of the skin …

The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration

AK Makuloluwa, KJ Hamill, S Rauz, L Bosworth… - The Ocular Surface, 2023 - Elsevier
The conjunctiva can be damaged by numerous diseases with scarring, loss of tissue and
dysfunction. Depending on extent of damage, restoration of function may require a …

[HTML][HTML] Validation of a clinical assessment tool for cicatrising conjunctivitis

HS Ong, D Minassian, S Rauz, JS Mehta, JK Dart - The ocular surface, 2020 - Elsevier
Purpose This study was designed to validate a semi-quantitative clinical assessment tool for
cicatrising conjunctivitis (CC). Methods Fifty-five patients (109 eyes) with mucous membrane …

[HTML][HTML] Rituximab therapy for mucous membrane pemphigoid: a retrospective monocentric study with long-term follow-up in 109 patients

G Bohelay, M Alexandre, C Le Roux-Villet… - Frontiers in …, 2022 - frontiersin.org
Mucous membrane pemphigoid (MMP) is a heterogeneous group of rare, chronic,
subepithelial autoimmune blistering diseases (AIBDs) with predominant involvement of …

Diagnostic relevance of direct immunofluorescence in ocular mucous membrane pemphigoid

T Mehra, E Guenova, F Dechent… - JDDG: Journal der …, 2015 - Wiley Online Library
Background and objectives The objective was to determine the diagnostic value of direct
immunofluorescence (DIF) in ocular mucous membrane pemphigoid (ocular MMP), taking …

[HTML][HTML] Ocular-Surface Regeneration Therapies for Eye Disorders: The State of the Art

M Posarelli, D Romano, D Tucci, G Giannaccare… - BioTech, 2023 - mdpi.com
The ocular surface is a complex structure that includes cornea, conjunctiva, limbus, and tear
film, and is critical for maintaining visual function. When the ocular-surface integrity is altered …

[HTML][HTML] Conjunctival neutrophils predict progressive scarring in ocular mucous membrane pemphigoid

GP Williams, P Nightingale… - … & visual science, 2016 - iovs.arvojournals.org
Purpose: Ocular mucous membrane pemphigoid (OcMMP) is a rare autoimmune disorder
resulting in progressive conjunctival fibrosis and ocular surface failure leading to sight loss …

Conceptualization of flow and transport in a limestone aquifer by multiple dedicated hydraulic and tracer tests

K Mosthaf, B Brauns, AS Fjordbøge, MM Rohde… - Journal of …, 2018 - Elsevier
Limestone aquifers are of great interest as a drinking water resource in many countries.
They often have a complex crushed and fractured geology, which makes the analysis and …