Advances in lymphedema

SG Rockson - Circulation research, 2021 - Am Heart Assoc
Lymphedema is a common, complex, and inexplicably underappreciated human disease.
Despite a history of relative neglect by health care providers and by governmental health …

Current mechanistic understandings of lymphedema and lipedema: tales of fluid, fat, and fibrosis

BH Duhon, TT Phan, SL Taylor, RL Crescenzi… - International Journal of …, 2022 - mdpi.com
Lymphedema and lipedema are complex diseases. While the external presentation of
swollen legs in lower-extremity lymphedema and lipedema appear similar, current …

Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves

I Spera, N Cousin, M Ries, A Kedracka, A Castillo… - …, 2023 - thelancet.com
Background Routes along the olfactory nerves crossing the cribriform plate that extend to
lymphatic vessels within the nasal cavity have been identified as a critical cerebrospinal fluid …

Interactions between nanoparticles and lymphatic systems: Mechanisms and applications in drug delivery

Y Tang, B Liu, Y Zhang, Y Liu, Y Huang… - Advanced Drug Delivery …, 2024 - Elsevier
The lymphatic system has garnered significant attention in drug delivery research due to the
advantages it offers, such as enhancing systemic exposure and enabling lymph node …

NIR-II fluorescence imaging for the detection and resection of cancerous foci and lymph nodes in early-stage orthotopic and advanced-stage metastatic ovarian …

T Pu, Y Liu, Y Pei, J Peng, Z Wang, M Du… - … Applied Materials & …, 2023 - ACS Publications
The high mortality rate of ovarian cancer can be primarily attributed to late diagnosis and
early lymph node (LN) metastasis. The anatomically deep-located ovaries own intricate …

Microfluidic‐Based Reconstitution of Functional Lymphatic Microvasculature: Elucidating the Role of Lymphatics in Health and Disease

JC Serrano, MR Gillrie, R Li, SH Ishamuddin… - Advanced …, 2024 - Wiley Online Library
The knowledge of the blood microvasculature and its functional role in health and disease
has grown significantly attributable to decades of research and numerous advances in cell …

Advances in photoacoustic imaging aided by nano contrast agents: special focus on role of lymphatic system imaging for cancer theranostics

B Sridharan, HG Lim - Journal of Nanobiotechnology, 2023 - Springer
Photoacoustic imaging (PAI) is a successful clinical imaging platform for management of
cancer and other health conditions that has seen significant progress in the past decade …

NIR-II fluorescence lymphatic imaging and intraoperative navigation based on the “isolated cage” monodisperse strategy

S Qi, Y Wang, Y Zhu, X Zhang, X Wang, X Yu, K Yang… - Nano Today, 2023 - Elsevier
Fluorescence imaging in the second near-infrared (NIR-II) window is well suited for
biological systems due to lower tissue scattering and micrometer-scale resolution at depths …

Protein@ cyanine‐based NIR‐II lymphography enables the supersensitive visualization of lymphedema and tumor lymphatic metastasis

J Xu, Y Du, T Han, N Zhu, S Zhu - Advanced Healthcare …, 2023 - Wiley Online Library
Visualization of the lymphatic system is clinically indispensable for the diagnosis and/or
treatment of lymphatic diseases. Although indocyanine green (ICG) lymphography becomes …

Intrathecal [64Cu]Cu-albumin PET reveals age-related decline of lymphatic drainage of cerebrospinal fluid

A Sarker, M Suh, Y Choi, JY Park, YS Lee, DS Lee - Scientific Reports, 2023 - nature.com
Age-related cognitive decline is associated with dysfunctional lymphatic drainage of
cerebrospinal fluid (CSF) through meningeal lymphatic vessels. In this study, intrathecal …