Pediatric drug development: reviewing challenges and opportunities by tracking innovative therapies
C Domingues, I Jarak, F Veiga, M Dourado, A Figueiras - Pharmaceutics, 2023 - mdpi.com
The paradigm of pediatric drug development has been evolving in a “carrot-and-stick”-based
tactic to address population-specific issues. However, the off-label prescription of adult …
tactic to address population-specific issues. However, the off-label prescription of adult …
The advantage of using immunoinformatic tools on vaccine design and development for coronavirus
J García-Machorro, GL Ramírez-Salinas… - Vaccines, 2022 - mdpi.com
After the outbreak of SARS-CoV-2 by the end of 2019, the vaccine development strategies
became a worldwide priority. Furthermore, the appearances of novel SARS-CoV-2 variants …
became a worldwide priority. Furthermore, the appearances of novel SARS-CoV-2 variants …
Novel nanocarriers for silencing anti-phagocytosis CD47 marker in acute myeloid leukemia cells
EM Hassan, S Zou - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
Acute myeloid leukemia (AML), a malignant disorder of Hematopoietic stem cells, can
escape immunosurveillance by over expression of the cluster of differentiation 47 (CD47) …
escape immunosurveillance by over expression of the cluster of differentiation 47 (CD47) …
PAMAM-G4 protect the N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) and maintain its antiproliferative effects on MCF-7
AA Ortiz-Morales, JB García-Vázquez… - Scientific Reports, 2023 - nature.com
Our work group designed and synthesized a promissory compound N-(2-hydroxyphenyl)-2-
propylpentanamide (HO-AAVPA). The HO-AAVPA is a HDAC1 inhibitor and antiproliferative …
propylpentanamide (HO-AAVPA). The HO-AAVPA is a HDAC1 inhibitor and antiproliferative …
Polyamidoamine dendrimers of the third generation–chlorin e6 nanoconjugates: Nontoxic hybrid polymers with photodynamic activity
CF Díaz, L Guzmán, VA Jiménez… - Journal of Applied …, 2022 - Wiley Online Library
Dendrimer‐based nanoconjugates play a key role as functional polymers for biomedical
applications. In this work, the one‐pot conjugation of polyamidoamine dendrimers of the …
applications. In this work, the one‐pot conjugation of polyamidoamine dendrimers of the …
Evidence That a Peptide-Drug/p53 Gene Complex Promotes Cognate Gene Expression and Inhibits the Viability of Glioblastoma Cells
Glioblastoma multiform (GBM) is considered the deadliest brain cancer. Conventional
therapies are followed by poor patient survival outcomes, so novel and more efficacious …
therapies are followed by poor patient survival outcomes, so novel and more efficacious …
Enhancement of octreotide antiproliferative activity by PEGylated PAMAM dendrimers delivery
CF Díaz, DL Cifuentes, M Oyarzún… - Journal of Applied … - Wiley Online Library
Abstract PEGylated PAMAM dendrimers (PEG‐PAMAM) are well‐characterized biomaterials
with still unexplored applications as carriers of drugs acting via membrane receptors, such …
with still unexplored applications as carriers of drugs acting via membrane receptors, such …
[PDF][PDF] Mini Review: Mass Spectrometry Technology for Molecule Distribution inside Skin
Z Hao - Adv. Res. Derm. Cosmet, 2022 - corpuspublishers.com
The functional ingredients for skin-related products have been highly recognized
accompanied by the consumers' curiosity and instrumental improvement. The targeted …
accompanied by the consumers' curiosity and instrumental improvement. The targeted …
[引用][C] Cinnamic acid terminated dendrimers–Synthesis, characterization, biological evaluation and NMR metabolomics analysis
ACD Olival - 2022