Hemocompatibility challenge of membrane oxygenator for artificial lung technology

BPN Thi, BTD Nguyen, IS Jeong, JF Kim - Acta Biomaterialia, 2022 - Elsevier
The artificial lung (AL) technology is one of the membrane-based artificial organs that partly
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …

[HTML][HTML] The roles of membrane technology in artificial organs: current challenges and perspectives

BT Duy Nguyen, HY Nguyen Thi, BP Nguyen Thi… - Membranes, 2021 - mdpi.com
The recent outbreak of the COVID-19 pandemic in 2020 reasserted the necessity of artificial
lung membrane technology to treat patients with acute lung failure. In addition, the aging …

[HTML][HTML] Pediatric and neonatal extracorporeal life support: current state and continuing evolution

BP Fallon, SK Gadepalli, RB Hirschl - Pediatric Surgery International, 2021 - Springer
The use of extracorporeal life support (ECLS) for the pediatric and neonatal population
continues to grow. At the same time, there have been dramatic improvements in the …

Shape design of an artificial pump-lung using high-resolution hemodynamic simulation with high-performance computing

W Chen, H Zheng, Z Yan, R Chen - Physics of Fluids, 2023 - pubs.aip.org
Accurate and fast prediction of the hemodynamics of the artificial pump-lung is critical in the
design process. In this study, a comprehensive computational framework, including a sliding …

Advances in extracorporeal membrane oxygenator design for artificial placenta technology

DG Blauvelt, EN Abada, P Oishi, S Roy - Artificial organs, 2021 - Wiley Online Library
Extreme prematurity, defined as a gestational age of fewer than 28 weeks, is a significant
health problem worldwide. It carries a high burden of mortality and morbidity, in large part …

Ambulatory 7-day mechanical circulatory support in sheep model of pulmonary hypertension and right heart failure

R Ukita, YJ Patel, WK Wu, SA Francois… - The Journal of Heart and …, 2024 - Elsevier
Background Right heart failure is the major cause of death in pulmonary hypertension. Lung
transplantation is the only long-term treatment option for patients who fail medical therapy …

[HTML][HTML] Artificial lungs: current status and future directions

RA Orizondo, AJ Cardounel, R Kormos… - Current Transplantation …, 2019 - Springer
Abstract Purpose of Review Although lung transplantation can be used to treat lung failure,
limited donor organ availability creates a pressing need for improved artificial lung …

Pilot testing of a lightweight, pulmonary assist system in an ambulatory sheep model of destination therapy respiratory support

KG Roberts, N Umei, S Shin, A Lai, EM Comber… - ASAIO …, 2024 - journals.lww.com
Abstract A new, lightweight (2.3 kg), ambulatory pulmonary assist system (PAS) underwent
preliminary evaluation in ambulatory sheep. The PAS was purposefully designed for long …

Month-long respiratory support by a wearable pumping artificial lung in an ovine model

RA Orizondo, KS Omecinski, AG May… - …, 2021 - journals.lww.com
Background. A wearable artificial lung could improve lung transplantation outcomes by
easing implementation of physical rehabilitation during long-term pretransplant respiratory …

Research progress of portable extracorporeal membrane oxygenation

Y Chen, D Li, Z Liu, Y Liu, H Fan… - Expert Review of Medical …, 2023 - Taylor & Francis
Introduction Extracorporeal membrane oxygenation (ECMO) is primarily used for the
supportive treatment of patients suffering from severe cardiopulmonary failure. With the …