Recent advances in nanoparticle applications in respiratory disorders: a review

ME Taghavizadeh Yazdi, M Qayoomian… - Frontiers in …, 2023 - frontiersin.org
Various nanoparticles are used in the discovery of new nanomedicine to overcome the
shortages of conventional drugs. Therefore, this article presents a comprehensive and up-to …

Aerosol pulmonary immune engineering

ER Sudduth, M Trautmann-Rodriguez, N Gill… - Advanced Drug Delivery …, 2023 - Elsevier
Aerosolization of immunotherapies poses incredible potential for manipulating the local
mucosal-specific microenvironment, engaging specialized pulmonary cellular defenders …

Macrophage implication in IPF: updates on immune, epigenetic, and metabolic pathways

D Pokhreal, B Crestani, DG Helou - Cells, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a lethal interstitial lung disease of unknown etiology
with a poor prognosis. It is a chronic and progressive disease that has a distinct radiological …

Induced pluripotent stem cells modulate the Wnt pathway in the bleomycin-induced model of idiopathic pulmonary fibrosis

P Bayati, M Taherian, M Soleimani, H Farajifard… - Stem Cell Research & …, 2023 - Springer
Abstract Background The Wnt signaling pathway has been implicated in the pathogenesis of
fibrotic disorders and malignancies. Hence, we aimed to assess the potential of the induced …

Mesenchymal cells in the Lung: Evolving concepts and their role in fibrosis

G Ligresti, AA Raslan, J Hong, N Caporarello… - Gene, 2023 - Elsevier
Mesenchymal cells in the lung are crucial during development, but also contribute to the
pathogenesis of fibrotic disorders, including idiopathic pulmonary fibrosis (IPF), the most …

Advances in the Use of N-Acetylcysteine in Chronic Respiratory Diseases

D Mokra, J Mokry, R Barosova, J Hanusrichterova - Antioxidants, 2023 - mdpi.com
N-acetylcysteine (NAC) is widely used because of its mucolytic effects, taking part in the
therapeutic protocols of cystic fibrosis. NAC is also administered as an antidote in …

Ginsenosides: a potential natural medicine to protect the lungs from lung cancer and inflammatory lung disease

L Wang, Y Zhang, Z Song, Q Liu, D Fan, X Song - Food & Function, 2023 - pubs.rsc.org
Lung cancer is the malignancy with the highest morbidity and mortality. Additionally,
pulmonary inflammatory diseases, such as pneumonia, acute lung injury, chronic obstructive …

Roles of exosomes and exosome-derived miRNAs in pulmonary fibrosis

Y Yang, H Huang, Y Li - Frontiers in Pharmacology, 2022 - frontiersin.org
Pulmonary fibrosis is a chronic, progressive fibrosing interstitial lung disease of unknown
etiology that leads rapidly to death. It is characterized by the replacement of healthy tissue …

Recent advances in intestinal fibrosis

MV Lenti, G Santacroce, G Broglio, CM Rossi… - Molecular Aspects of …, 2024 - Elsevier
Despite many progresses have been made in the treatment of inflammatory bowel disease,
especially due to the increasing number of effective therapies, the development of tissue …

The role of macrophages in connective tissue disease-associated interstitial lung disease: focusing on molecular mechanisms and potential treatment strategies

CC Tseng, YW Sung, KY Chen, PY Wang… - International Journal of …, 2023 - mdpi.com
Connective tissue disease-associated interstitial lung disease (CTD-ILD) is a severe
manifestation of CTD that leads to significant morbidity and mortality. Clinically, ILD can …