Prevalence and Therapies of Antibiotic-Resistance in Staphylococcus aureus

Y Guo, G Song, M Sun, J Wang… - Frontiers in cellular and …, 2020 - frontiersin.org
Infectious diseases are the second most important cause of human death worldwide;
Staphylococcus aureus (S. aureus) is a very common human pathogenic microorganism that …

Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens

E Peterson, P Kaur - Frontiers in microbiology, 2018 - frontiersin.org
Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

Antibiotic resistance genes in bacteria: Occurrence, spread, and control

Z Jian, L Zeng, T Xu, S Sun, S Yan… - Journal of basic …, 2021 - Wiley Online Library
The production and use of antibiotics are becoming increasingly common worldwide, and
the problem of antibiotic resistance is increasing alarmingly. Drug‐resistant infections …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Antibiotic discovery and resistance: the chase and the race

K Iskandar, J Murugaiyan, D Hammoudi Halat… - Antibiotics, 2022 - mdpi.com
The history of antimicrobial resistance (AMR) evolution and the diversity of the
environmental resistome indicate that AMR is an ancient natural phenomenon. Acquired …

Antibiotic resistance and the MRSA problem

M Vestergaard, D Frees, H Ingmer - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically
available and resistance can develop through de novo mutations in chromosomal genes or …

The spread of antibiotic resistance genes in vivo model

S Tao, H Chen, N Li, T Wang… - Canadian Journal of …, 2022 - Wiley Online Library
Infections caused by antibiotic‐resistant bacteria are a major public health threat. The
emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical …

Effects and relevant mechanisms of non-antibiotic factors on the horizontal transfer of antibiotic resistance genes in water environments: A review

Q Jiang, M Feng, C Ye, X Yu - Science of The Total Environment, 2022 - Elsevier
Antibiotic resistance has created obstacles in the treatment of infectious diseases with
antibiotics. The horizontal transfer of antibiotic resistance genes (ARGs) can exacerbate the …

Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms

M Maree, LT Thi Nguyen, RL Ohniwa… - Nature …, 2022 - nature.com
SCC mec is a large mobile genetic element that includes the mecA gene and confers
resistance to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus (MRSA) …

Virulence factors in coagulase-negative staphylococci

A França, V Gaio, N Lopes, LDR Melo - Pathogens, 2021 - mdpi.com
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-
associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S …