The diagnosis and management of thyroid nodules: a review

C Durante, G Grani, L Lamartina, S Filetti, SJ Mandel… - Jama, 2018 - jamanetwork.com
Importance Thyroid nodules are common, being detected in up to 65% of the general
population. This is likely due to the increased use of diagnostic imaging for purposes …

Understanding the ever-changing incidence of thyroid cancer

CM Kitahara, JA Sosa - Nature Reviews Endocrinology, 2020 - nature.com
This Comment article provides a behind-the-scenes perspective and update of our 2016
Review, which discussed possible factors contributing to thyroid cancer incidence trends …

Performance of a multigene genomic classifier in thyroid nodules with indeterminate cytology: a prospective blinded multicenter study

DL Steward, SE Carty, RS Sippel, SP Yang… - JAMA …, 2019 - jamanetwork.com
Importance Approximately 20% of fine-needle aspirations (FNA) of thyroid nodules have
indeterminate cytology, most frequently Bethesda category III or IV. Diagnostic surgeries can …

Effectiveness of molecular testing techniques for diagnosis of indeterminate thyroid nodules: a randomized clinical trial

MJ Livhits, CY Zhu, EJ Kuo, DT Nguyen, J Kim… - JAMA …, 2021 - jamanetwork.com
Importance Approximately 20% of thyroid nodules display indeterminate cytology. Molecular
testing can refine the risk of malignancy and reduce the need for diagnostic …

Impact of overweight and obesity on US papillary thyroid cancer incidence trends (1995–2015)

CM Kitahara, RM Pfeiffer, JA Sosa… - JNCI: Journal of the …, 2020 - academic.oup.com
Background Since the early 1980s, papillary thyroid cancer (PTC) incidence rates and the
prevalence of obesity, a risk factor for PTC, have increased substantially in the United …

Afirma gene sequencing classifier compared with gene expression classifier in indeterminate thyroid nodules

M Endo, F Nabhan, K Porter, K Roll, LA Shirley… - Thyroid, 2019 - liebertpub.com
Background: The Afirma Gene Expression Classifier (GEC) has been used to further
characterize cytologically indeterminate (cyto-I) thyroid nodules into either benign or …

Thyroid nodules: diagnostic evaluation based on thyroid cancer risk assessment

NS Ospina, NM Iñiguez-Ariza, MR Castro - bmj, 2020 - bmj.com
Thyroid nodules are extremely common and can be detected by sensitive imaging in more
than 60% of the general population. They are often identified in patients without symptoms …

Clinical safety of renaming encapsulated follicular variant of papillary thyroid carcinoma: is NIFTP truly benign?

DN Parente, WP Kluijfhout, PJ Bongers… - World Journal of …, 2018 - Wiley Online Library
Background Renaming encapsulated follicular variant of papillary thyroid carcinoma
(EFVPTC) to noninvasive follicular thyroid neoplasm with papillary‐like nuclear features …

[HTML][HTML] Differential MicroRNA-signatures in thyroid cancer subtypes

K Santiago, Y Chen Wongworawat, S Khan - Journal of Oncology, 2020 - hindawi.com
Thyroid cancer is one of the most common endocrine cancers, with an increasing trend in
the last few decades. Although papillary thyroid cancer is the most frequent subtype …

[18F]FDG-PET/CT to prevent futile surgery in indeterminate thyroid nodules: a blinded, randomised controlled multicentre trial

EJ de Koster, LF de Geus-Oei, AH Brouwers… - European Journal of …, 2022 - Springer
Purpose To assess the impact of an [18 F] FDG-PET/CT-driven diagnostic workup to rule out
malignancy, avoid futile diagnostic surgeries, and improve patient outcomes in thyroid …