The regulatory functions of the immune response in tissue healing, repair, and regeneration
have been evidenced in the last decade. Immune cells play central roles in immune …

Cardiovascular disease is the leading cause of mortality and morbidity around the globe,
creating a substantial socio-economic burden as a result. Myocardial infarction is a …

Abstract Aims N6-Methyladenosine (m 6 A), one of the important epigenitic modifications, is
very commom in messenger RNAs (mRNAs) of eukaryotes, and has been involved in …

Xenotransplantation using pig organs has achieved survival times up to 195 days in pig
orthotopic heart transplantation into baboons. Here we demonstrate that in addition to an …

Rationale: Despite recent studies indicating a crucial role of ecto-5′-nucleotidase (CD73)
on T cells in cardiac injury after ischemia/reperfusion, the involvement of CD73+ regulatory T …

Heart injury such as myocardial infarction leads to cardiomyocyte loss, fibrotic tissue
deposition, and scar formation. These changes reduce cardiac contractility, resulting in heart …

Aims Newborn mice and humans display transient cardiac regenerative potential that rapidly
declines postnatally. Patients who survive a myocardial infarction (MI) often develop chronic …

Implementing Single-cell RNA sequencing (scRNA-seq) has significantly enhanced our
comprehension of cardiovascular diseases (CVDs), providing new opportunities to …

The lymphatic network of mammalian heart is an important regulator of interstitial fluid
compartment and immune cell trafficking. We observed a remodeling of the cardiac …

Myocardial infarction (MI) is a cardiovascular disease (CVD) with high morbidity and
mortality worldwide, often leading to adverse cardiac remodeling and heart failure, which is …