Carnitine and acylcarnitines: pharmacokinetic, pharmacological and clinical aspects

SE Reuter, AM Evans - Clinical pharmacokinetics, 2012 - Springer
L-Carnitine (levocarnitine) is a naturally occurring compound found in all mammalian
species. The most important biological function of L-carnitine is in the transport of fatty acids …

Carnitine inborn errors of metabolism

M Almannai, M Alfadhel, AW El-Hattab - Molecules, 2019 - mdpi.com
Carnitine plays essential roles in intermediary metabolism. In non-vegetarians, most of
carnitine sources (~ 75%) are obtained from diet whereas endogenous synthesis accounts …

[HTML][HTML] Skeletal muscle dysfunction in chronic renal failure: effects of exercise

GR Adams, ND Vaziri - American Journal of Physiology …, 2006 - journals.physiology.org
A number of chronic illnesses such as renal failure (CRF), obstructive pulmonary disease,
and congestive heart failure result in a significant decrease in exercise tolerance. There is …

Significance of levocarnitine treatment in dialysis patients

H Takashima, T Maruyama, M Abe - Nutrients, 2021 - mdpi.com
Carnitine is a naturally occurring amino acid derivative that is involved in the transport of
long-chain fatty acids to the mitochondrial matrix. There, these substrates undergo β …

Levocarnitine improves cardiac function in hemodialysis patients with left ventricular hypertrophy: a randomized controlled trial

T Higuchi, M Abe, T Yamazaki, E Okawa… - American Journal of …, 2016 - Elsevier
Background Levocarnitine deficiency in hemodialysis patients is common. Although the
effect of levocarnitine therapy on uremic anemia has been studied in small trials, its effects …

Levocarnitine and dialysis: a review

B Schreiber - Nutrition in clinical practice, 2005 - Wiley Online Library
Among the various metabolic abnormalities documented in dialysis patients are
abnormalities related to the metabolism of fatty acids. Aberrant fatty‐acid metabolism has …

Nutritional management of children with acute kidney injury—clinical practice recommendations from the Pediatric Renal Nutrition Taskforce

MRW Vega, D Cerminara, A Desloovere… - Pediatric …, 2023 - Springer
The nutritional management of children with acute kidney injury (AKI) is complex. The
dynamic nature of AKI necessitates frequent nutritional assessments and adjustments in …

Simultaneous determination of phosphatidylcholine-derived quaternary ammonium compounds by a LC–MS/MS method in human blood plasma, serum and urine …

C Steuer, P Schütz, L Bernasconi, AR Huber - Journal of Chromatography B, 2016 - Elsevier
The determination of circulating trimethylamine-N-oxide (TMAO), choline, betaine, l-carnitine
and O-acetyl-l-carnitine concentration in different human matrices is of great clinical interest …

Carnitine in maintenance hemodialysis patients

G Guarnieri - Journal of Renal Nutrition, 2015 - Elsevier
Carnitine is a conditionally essential metabolite that plays a critical role in cell physiology.
Carnitine is necessary for fatty acid transport to sites of beta-oxidation in the mitochondria …

Effects of levocarnitine on brachial-ankle pulse wave velocity in hemodialysis patients: a randomized controlled trial

T Higuchi, M Abe, T Yamazaki, M Mizuno, E Okawa… - Nutrients, 2014 - mdpi.com
Background and Aims: Atherosclerotic cardiovascular disease is the most common cause of
mortality in patients with end-stage kidney disease. Chronic kidney disease patients often …