One‐Pot Multicomponent Reaction: A Highly Versatile Strategy for the Construction of Valuable Nitrogen‐Containing Heterocycles
A large portion of the chemical subspace is the multi‐component reaction (MCR). Apart from
Domino reactions, MCR is one of the most promising routes for one‐pot synthesis. Thus …
Domino reactions, MCR is one of the most promising routes for one‐pot synthesis. Thus …
[HTML][HTML] Synthetic strategies of heterocycle-integrated pyridopyrimidine scaffolds supported by nano-catalysts
Nano-catalysts are of special character for the synthesis of organic molecules with high
efficiency, and exceptional physicochemical properties. The objective of this study was to …
efficiency, and exceptional physicochemical properties. The objective of this study was to …
One‐pot and two‐pot methods for chalcone derived pyrimidines synthesis and applications
S Farooq, Z Ngaini - Journal of Heterocyclic Chemistry, 2021 - Wiley Online Library
Chalcone‐derived pyrimidine is a well‐known heterocyclic compound that is commonly
present in ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) bio‐isosteres …
present in ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) bio‐isosteres …
Recent Developments in the MCRs Synthesis of Pyridopyrimidines and Spiro‐Pyridopyrimidines
M Mamaghani, R Hossein Nia - Journal of Heterocyclic …, 2017 - Wiley Online Library
Because of biological and medicinal properties of pyridopyrimidines, synthesis of these
heterocycles has attracted the interest of organic and medicinal chemists. This review …
heterocycles has attracted the interest of organic and medicinal chemists. This review …
Recent progress in the chemistry of bicyclic 6–6 systems: chemistry of pyrido[1,2-a]pyrimidines
KM Elattar, R Rabie, MM Hammouda - Monatshefte für Chemie-Chemical …, 2017 - Springer
The present review provides a study on the structural features, reactions, and synthetic
methodologies of pyrido [1, 2-a] pyrimidines. Thus, the synthetic procedures and organic …
methodologies of pyrido [1, 2-a] pyrimidines. Thus, the synthetic procedures and organic …
Mild, General, and Regioselective Synthesis of 2-Aminopyridines from Pyridine N-Oxides via N-(2-Pyridyl) pyridinium Salts
H Xiong, AT Hoye - Synlett, 2022 - thieme-connect.com
A synthesis of 2-aminopyridines from pyridine N-oxides via their corresponding N-(2-pyridyl)
pyridinium salts has been demonstrated and investigated. The reaction sequence features a …
pyridinium salts has been demonstrated and investigated. The reaction sequence features a …
Transition metal-free one-pot synthesis of nitrogen-containing heterocycles
One-pot heterocyclic synthesis is an exciting research area as it can open routes for the
development of otherwise complex transformations in organic synthesis. Heterocyclic …
development of otherwise complex transformations in organic synthesis. Heterocyclic …
Naturally inspired pyrimidines analogues for alzheimer's disease
S Singh, M Dhanawat, S Gupta… - Current …, 2021 - ingentaconnect.com
Alzheimer's disease (AD) is a multifarious and developing neurodegenerative disorder. The
treatment of AD is still a challenge and availability of drug therapy on the basis of symptoms …
treatment of AD is still a challenge and availability of drug therapy on the basis of symptoms …
Discovery of novel tricyclic thiazepine derivatives as anti-drug-resistant cancer agents by combining diversity-oriented synthesis and converging screening approach
J Xiang, Z Zhang, Y Mu, X Xu, S Guo, Y Liu… - ACS combinatorial …, 2016 - ACS Publications
An efficient discovery strategy by combining diversity-oriented synthesis and converging
cellular screening is described. By a three-round screening process, we identified novel …
cellular screening is described. By a three-round screening process, we identified novel …
[HTML][HTML] The Flögel-three-component reaction with dicarboxylic acids–an approach to bis (β-alkoxy-β-ketoenamides) for the synthesis of complex pyridine and …
MK Bera, M Domínguez, P Hommes… - Beilstein Journal of …, 2014 - beilstein-journals.org
An extension of the substrate scope of the Flögel-three-component reaction of lithiated
alkoxyallenes, nitriles and carboxylic acids is presented. The use of dicarboxylic acids …
alkoxyallenes, nitriles and carboxylic acids is presented. The use of dicarboxylic acids …