Ubiquitin E3 ligases are the most prevalent cancer genes besides protein kinases,
suggesting a critical role in cancer development and progression. Two major classes of E3 …

There is provided the use of disulfiram and analogs thereof to inhibit catalytic activity.
Additionally, dithioperoxothioates can be used to inhibit catalytic activity. More specifically …

Los carcinomas son los cánceres más comunes, se desarrollan por la transformación de
células epiteliales en mesenquimales. La principal causa de muerte en los pacientes con …

This issue marks the end of the 10-year anniversary of Neoplasia where we have seen
exciting growth in both number of submitted and published articles in Neoplasia. Neoplasia …

Breast cancer is one of the most common types of cancer after skin cancer. In India, for every
two women newly diagnosed with breast cancer, one woman dies because of it. The cause …

Over the past decades, tumor-resident immune cells have been extensively studied to
dissect their biological functions and clinical roles. Tumor-infiltrating CD8+ T cells, because …

RNF11 (RING finger protein 11) has been indicated to be related to numerous
immunological diseases. As a neo-regulator in innate immunity, RNF11 was proved to …

The struggle to find new cancer targets continues unabated. With this in mind, E3 ligases
(also called E3 ubiquitin ligases) constitute a large and diverse family of genes that play a …

The study of the interaction between a host and a viral antagonist is complex and essential
for developing targeted therapeutic measures against these viruses. The host has many …

Gene Section Page 1 Gene Section Review Atlas Genet Cytogenet Oncol Haematol. 2014;
18(2) 112 INIST-CNRS OPEN ACCESS JOURNAL Atlas of Genetics and Cytogenetics in …