Omicron SARS-CoV-2 is rapidly spreading worldwide. To delineate the impact of emerging
mutations on spike's properties, we performed systematic structural analyses on apo …

The Omicron BA. 1 variant emerged in late 2021 and quickly spread across the world.
Compared to the earlier SARS-CoV-2 variants, BA. 1 has many mutations, some of which …

Since the start of the coronavirus disease 2019 (COVID‐19) pandemic, new variants of
severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) have emerged …

Background Limited data are available on the effectiveness of inactivated and Ad5-nCoV
COVID-19 vaccines in real-world use—especially against Omicron variants in SARS-CoV-2 …

Background This phase 2b part of a randomized phase 2/3 study assessed the efficacy and
safety of ensitrelvir for mild-to-moderate coronavirus disease 2019 (COVID-19) during the …

Although the chief of the World Health Organization (WHO) has declared the end of the
coronavirus disease 2019 (COVID-19) as a global health emergency, the disease is still a …

The Omicron BA. 1 variant of SARS-CoV-2 escapes convalescent sera and monoclonal
antibodies that are effective against earlier strains of the virus. This immune evasion is …

With the emergence and rapid spread of new pandemic variants, especially variants of
concern (VOCs), the development of next-generation vaccines with broad-spectrum …

Objectives We compared the vaccine effectiveness over time of the primary series and
booster against infection and severe disease with the Delta, Omicron BA. 1, and BA. 2 …

Abstract The Coronavirus Disease 2019 (COVID-19) pandemic continues to infect people
worldwide. While the vaccinated population has been increasing, the rising breakthrough …