Epidermolysis bullosa (EB) is an inherited, heterogeneous group of rare genetic dermatoses
characterized by mucocutaneous fragility and blister formation, inducible by often minimal …

Heritable predisposition is an important cause of cancer in children and adolescents.
Although a large number of cancer predisposition genes and their associated syndromes …

Epidermolysis bullosa (EB) is a heterogeneous group of inherited skin disorders determined
by mutations in genes encoding for structural components of the cutaneous basement …

Background/objective Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic
collagen disorder characterized by skin fragility leading to blistering, wounds, and scarring …

Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is
known about how it predisposes the tissue microenvironment preceding tumor formation …

The phenotypic presentation of monogenetic diseases is determined not only by the nature
of the causative mutations but also is influenced by manifold cellular, microenvironmental …

Recessive dystrophic epidermolysis bullosa (RDEB) is a skin fragility disease caused by
mutations that affect the function and/or the amount of type VII collagen (C7), the major …

Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a devastating skin blistering disease
caused by mutations in the gene encoding type VII collagen (C7), leading to epidermal …

Chronic wounds are a significant challenge for patients, healthcare providers, and
healthcare systems. Chronic wounds develop due to a complex interplay between chronic …

Epidermolysis bullosa (EB), notably severe recessive dystrophic EB (RDEB-S), is associated
with increased risk of aggressive mucocutaneous squamous cell carcinomas, the major …