Current gene-editing approaches for treatment of recessive dystrophic epidermolysis
bullosa (RDEB), an inherited, severe form of blistering skin disease, suffer from low …

Epidermolysis Bullosa (EB) is a group of rare genetic disorders resulting in skin fragility and
other symptoms. Commissioned by DEBRA International and funded by DEBRA Norway …

Epidermolysis bullosa (EB) is a group of rare congenital diseases caused by mutations in
structural proteins of the dermal/epidermal junction that are characterized by extreme …

The term epidermolysis bullosa (EB) refers to a group of hereditary skin blistering diseases.
The group is clinically and genetically heterogeneous, but all EB forms are associated with …

End-joining‒based gene editing is frequently used for efficient reframing and knockout of
target genes. However, the associated random, unpredictable, and often heterogeneous …

Epidermolysis bullosa (EB) is a severe hereditary disease characterized by defective
epithelial adhesion causing mucocutaneous fragility. The major types are EB simplex (EBS) …

Epidermolysis bullosa (EB) is a group of devastating genetic diseases characterized by skin
and mucosal fragility and formation of blisters, which develop either spontaneously or in …

Background Epidermolysis bullosa (EB) is a disabling and chronic genodermatosis
characterized by mucocutaneous fragility with blister formation after minimal trauma …

Dystrophic epidermolysis bullosa is a heritable skin disease manifesting with sub-lamina
densa blistering, erosions, and chronic ulcers. COL7A1, encoding type VII collagen, has …

Gene editing via homology-directed repair (HDR) currently comprises the best strategy to
obtain perfect corrections for pathogenic mutations of monogenic diseases, such as the …