Gastro-oesophageal reflux disease (GERD) is a common disorder in adults and children.
The global prevalence of GERD is high and increasing. Non-erosive reflux disease is the …

Background An international group of experts evaluated and revised recommendations for
ambulatory reflux monitoring for the diagnosis of gastro‐esophageal reflux disease (GERD) …

Presenting breakthrough research pertinent to scientists in a wide range of disciplines-from
medicine and biotechnology to cosmetics and pharmacy-this Second Edition provides …

Nonerosive reflux disease (NERD) represents the more common phenotypic presentation of
GERD and comprises patients who have typical symptoms without any mucosal breaks at …

Sleep quality and sleep disorders affect symptom manifestation and the pathogenesis of
digestive diseases. Sleep is largely regulated by the light–dark cycle and associated …

Barrett's esophagus is associated with reflux disease and substantially increases the risk of
esophageal adenocarcinoma. The authors undertook a systematic review and meta …

Key Clinical Points Gastroesophageal Reflux Disease Patients with heartburn and
symptoms such as dysphagia, odynophagia, weight loss, anorexia, gastrointestinal …

OBJECTIVES: We sought to compare reflux and symptom association patterns in patients
with nonerosive reflux disease (NERD), erosive esophagitis (EE), and in healthy volunteers …

INTRODUCTION: Functional heartburn is defined by Rome III criteria as an endoscopy-
negative condition with normal oesophageal acid exposure time, negative symptom …

Nocturnal gastroesophageal reflux has been associated with poor sleep quality. Normal
physiological adaptations of the aerodigestive system to sleep prolong and intensify …