Interaction of SARS-CoV-2 with host cells and antibodies: experiment and simulation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …
[HTML][HTML] Could metabolomics drive the fate of COVID-19 pandemic? A narrative review on lights and shadows
Abstract Human Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2)
infection activates a complex interaction host/virus, leading to the reprogramming of the host …
infection activates a complex interaction host/virus, leading to the reprogramming of the host …
[HTML][HTML] High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike
Designing prefusion-stabilized SARS-CoV-2 spike is critical for the effectiveness of COVID-
19 vaccines. All COVID-19 vaccines in the US encode spike with K986P/V987P mutations to …
19 vaccines. All COVID-19 vaccines in the US encode spike with K986P/V987P mutations to …
[HTML][HTML] Ca2+-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide
G Khelashvili, A Plante, M Doktorova, H Weinstein - Biophysical Journal, 2021 - cell.com
Cell penetration after recognition of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) virus by the ACE2 receptor and the fusion of its viral envelope membrane …
(SARS-CoV-2) virus by the ACE2 receptor and the fusion of its viral envelope membrane …
Binding of SARS-CoV-2 fusion peptide to host endosome and plasma membrane
During infection the SARS-CoV-2 virus fuses its viral envelope with cellular membranes of
its human host. The viral spike (S) protein mediates both the initial contact with the host cell …
its human host. The viral spike (S) protein mediates both the initial contact with the host cell …
[HTML][HTML] Sterically confined rearrangements of SARS-CoV-2 Spike protein control cell invasion
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious, and
transmission involves a series of processes that may be targeted by vaccines and …
transmission involves a series of processes that may be targeted by vaccines and …
[HTML][HTML] COVID-19 and neurodegenerative diseases: prion-like spread and long-term consequences
N Baazaoui, K Iqbal - Journal of Alzheimer's Disease, 2022 - content.iospress.com
COVID-19 emerged as a global pandemic starting from Wuhan in China and spread at a
lightning speed to the rest of the world. One of the potential long-term outcomes that we …
lightning speed to the rest of the world. One of the potential long-term outcomes that we …
The constellation of cholesterol-dependent processes associated with SARS-CoV-2 infection
FJ Barrantes - Progress in lipid research, 2022 - Elsevier
The role of cholesterol in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and other coronavirus-host cell interactions is currently being discussed in the context of two …
and other coronavirus-host cell interactions is currently being discussed in the context of two …
Exploring the pH dependence of the SARS‐CoV‐2 complete fusion domain and the role of its unique structural features
D Birtles, AE Oh, J Lee - Protein Science, 2022 - Wiley Online Library
SARS‐CoV‐2 may enter target cells through the process of membrane fusion at either the
plasma (~ pH 7.4–7.0) or endosomal (~ pH 6.5–5.0) membrane in order to deliver its genetic …
plasma (~ pH 7.4–7.0) or endosomal (~ pH 6.5–5.0) membrane in order to deliver its genetic …
Host cell membrane capture by the SARS-CoV-2 spike protein fusion intermediate
R Su, J Zeng, TC Marcink, M Porotto… - ACS Central …, 2023 - ACS Publications
Cell entry by SARS-CoV-2 is accomplished by the S2 subunit of the spike S protein on the
virion surface by capture of the host cell membrane and fusion with the viral envelope …
virion surface by capture of the host cell membrane and fusion with the viral envelope …