Hepatitis C virus (HCV) affects approximately 268,000 Canadians and results in more years
of life lost than any other infectious disease in the country. Both the Canadian Institutes of …

Proteomics is the study of proteins and/or their interactions with other molecules in a
biological system. Proteomics is getting more and more popular due to the easy-to-use and …

Hepatitis C virus (HCV) remains a major global health burden, with more than 130 million
individuals chronically infected and at risk for the development of hepatocellular carcinoma …

Cellular chaperones that belong to the heat‐shock protein 90 (Hsp90) family are a
prerequisite for successful viral propagation for most viruses. The hepatitis C virus (HCV) …

Since cell regulation and protein expression can be dramatically altered upon infection by
viruses, studying the mechanisms by which viruses infect cells and the regulatory networks …

The functions of many viral proteins involve direct interactions with specific host proteins.
Therefore considerable insight into the functions of a viral protein and its mechanisms of …

Introduction: Many reports have evaluated the clinical efficacy and safety of the fixed-dose
all-oral combination of daclatasvir, asunaprevir, and beclabuvir (DCV-TRIO), which was …

Hepatitis C virus (HCV) currently infects over 185 million individuals around the world. Its
persistence causes infected individuals to enter a chronic phase where their condition can …

Hepatitis C virus (HCV) is a major cause of liver disease worldwide. Acute infection often
progresses to chronicity resulting frequently in fibrosis, cirrhosis, and in rare cases, in the …

Introduction: The introduction of direct-acting antiviral (DAA) agents has revolutionized the
treatment of hepatitis C virus (HCV) chronic infection. Non-structural 3 protease inhibitors …