An increasing proportion of curated host‐pathogen interaction (HPI) information is becoming
available in interaction databases. These data represent detailed, experimentally‐verified …

Viruses are obligate parasites that depend on cellular factors for replication.
Pharmacological inhibition of essential viral proteins, mostly enzymes, is an effective …

Proteomics and imaging techniques are used more and more in tandem to investigate the
virus-host interaction. Herein we present novel replicons, methods and trans-encapsidation …

ABSTRACT Poly (rC)-binding protein 2 (PCBP2) was previously shown to bind to the
hepatitis C virus (HCV) genome; however, its precise role in the viral life cycle remained …

This dissertation focuses on the host innate immune response in the context of hepatitis A
virus (HAV) and hepatitis C virus (HCV) infections in human hepatocytes. Innate immunity is …

The hepatitis C virus (HCV) is a positive-sense, single-stranded RNA virus; as such, its
genome directly participates in multiple mutually exclusive steps of the viral life cycle …

Viruses rely on host proteins to complete their life cycles. This results in alterations to normal
cell physiology to processes which benefit viral processes such as replication and …

Hepatitis C virus (HCV), a member of the genus Hepacivirus in the Flaviviridae family (1), is
a single‐stranded RNA virus that infects humans and other higher primates, and has a …

Unraveling host-pathogen interactions upon Mycobacterium tuberculosis infections using
quantitative mass spectrometry Page 1 DISS. ETH NO. 26776 Unraveling host-pathogen …

Human cytomegalovirus (HCMV) is a ubiquitous pathogen that infects the majority of the
adult population. Similarly to other herpesvirus, it is able to enter a state of latency, persisting …