From the first measurements of the distribution of pulmonary blood flow using radioactive
tracers by West and colleagues (J Clin Invest 40: 1–12, 1961) allowing gravitational …

This review will cover the principles of imaging the deposition of inhaled drugs and some of
the state-of-the art imaging techniques being used today. Aerosol deposition can be imaged …

Objective: Neutrophilic inflammation plays a key role in the pathogenesis of acute
respiratory distress syndrome (ARDS) and acute lung injury (ALI). Positron emission …

The ability to visualize molecular processes and cellular regulators of complex pulmonary
diseases such as asthma, chronic obstructive pulmonary disease (COPD), or adult …

Abstract Ventilation-perfusion (VA/Q) matching, the regional matching of the flow of fresh gas
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …

Cystic fibrosis (CF) is a common inherited condition caused by mutations in the gene
encoding the CF transmembrane regulator protein. With increased understanding of the …

We wanted to illustrate the feasibility of using hyperpolarized helium magnetic resonance
imaging (HPH-MRI) to obtain functional information that may assist in improving conformal …

Recent advances in imaging offer exciting opportunities to develop and validate lung-
specific biomarkers as valuable adjuncts to diagnosis, tests of treatment efficacy, and/or …

As far as setting positive end-expiratory pressure is concerned, further randomized clinical
studies are warranted to verify the pathophysiologic findings recently observed with …

New modalities in radiology hold promise to aid in the understanding and treatment of small-
airway disease. Although still considered investigational modalities, research evidence is …