The quantitative determination of xenobiotic compounds, as well as biotics in biological
matrices, is generally described with the term bioanalysis. Due to the complexity of biofluids …

Tricyclic antidepressants are commonly employed in the management of major depressive
disorders. The present work describes two visible (VIS) spectrophotometric techniques that …

The accurate measurement of drug concentration in patient samples is vital and is often
conducted using point of care devices for therapeutic drug monitoring and other clinical …

The effect of LC mobile phase composition and flow rate (2–50 µL/min) on mobility behavior
in vacuum differential mobility spectrometry (vDMS) was investigated for electrosprayed …

A solid phase extraction-based (SPE) procedure for simultaneous preconcentration of five
tricyclic antidepressants (TCAs), amitriptyline hydrochloride (AMT), nortriptyline …

A new method that allows organic acid selectivity to be dynamically controlled during gas
chromatography (GC) is presented. It employs dual in-series stainless steel columns, each …

Bioanalysis involves a broad range of chemical analyzes. These analyzes include that of
biotics, such as natural components of living organisms, as well as xenobiotics, such as …

Background: Anti-depressants are used to treat depression and some anxiety and
personality disorders. In this study, a magnetic sorbent was prepared for the extraction of …

Drug-facilitated sexual assaults are a public health and safety concern. Liquid
chromatography paired with tandem mass spectrometry is theoretically capable of detecting …

Tricyclic antidepressants such as doxepin have been usually implicated in human metabolic
disorders and weight gain. However, the exact mechanism by which antidepressants induce …