A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

The laws governing cannabis are evolving worldwide and associated with changing
patterns of use. The main psychoactive drug in cannabis is Δ 9-tetrahydrocannabinol (THC) …

Prospective epidemiological studies have consistently demonstrated that cannabis use is
associated with an increased subsequent risk of both psychotic symptoms and …

The past few decades have seen a marked change in the composition of commonly smoked
cannabis. These changes primarily involve an increase of the psychoactive compound∆ 9 …

The widespread use of MRI has led to a wealth of structural and functional anatomical
findings in patients with diverse psychiatric disorders that may represent insights into …

Aims To test, among US students:(1) whether perceived harmfulness of marijuana has
changed over time,(2) whether perceived harmfulness of marijuana changed post‐passage …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Regular cannabis use is associated with adverse cognitive and mental health outcomes that
have been ascribed to aberrant neuroanatomy in brain regions densely innervated with …

There have been dramatic changes worldwide in the attitudes toward and consumption of
recreational and medical cannabis. Cannabinoid receptors, which mediate the actions of …

Substance use disorders (SUDs) are characterized by a compulsion to seek and consume
one or more substances of abuse, with a perceived loss of control and a negative emotional …