Twenty years ago, Rho-kinase was identified as an important downstream effector of the
small GTP-binding protein, RhoA. Thereafter, a series of studies demonstrated the important …

The occurrence and development of cardiovascular complications are predominantly
responsible for the increased morbidity and mortality observed in patients with diabetes …

Rho-associated coiled-coil kinase (ROCK) is a major downstream effector of the small
GTPase RhoA. The ROCK family, consisting of ROCK1 and ROCK2, plays a central role in …

The HMG Co-enzyme inhibitors and new lipid-modifying agents expand their new
therapeutic target options in the field of medical profession. Statins have been described as …

Vascular smooth muscle (VSM) plays an important role in the regulation of vascular function.
Identifying the mechanisms of VSM contraction has been a major research goal in order to …

Diabetes is a worldwide health issue closely associated with cardiovascular events. Given
the pandemic of obesity, the identification of the basic underpinnings of vascular disease is …

Glaucoma is a leading cause of irreversible blindness worldwide. Elevated intraocular
pressure (IOP) is considered to be a predominant risk factor for primary open angle …

Hypertensive cardiac remodeling is characterized by left ventricular hypertrophy and
interstitial fibrosis, which can lead to heart failure with preserved ejection fraction. The Rho …

Statins, known as HMG-CoA reductase (HMGCR) inhibitors, have primarily been utilized for
metabolic and angiographic medical applications because of their cholesterol-lowering …

Pravastatin for Preventing and Treating Preeclampsia: A Syst... : Obstetrical & Gynecological
Survey Pravastatin for Preventing and Treating Preeclampsia: A Systematic Review …