Protective effects of Schisandrin on high glucose-induced changes of RhoA and eNOS activity in human umbilical vein endothelial cells

RJ Zhang, HY Hao, QJ Liu, HY Zuo, YN Chang… - … -Research and Practice, 2018 - Elsevier
Schisandrin, derived from the Chinese medicinal herb Schisandra chinensis, has been
found to confer protective effects on circulation systems. But the underlying molecular …

[PDF][PDF] Research progress on diagnosis and treatment of atherosclerosis

R Basnet, S Khadka, Y Wang, R Gupta - Science Letters, 2020 - researchgate.net
The cardiovascular diseases are one of the leading causes of death worldwide. Despite
preventive measures, early detection and common pathophysiological mechanisms of …

[HTML][HTML] 人血浆脂蛋白相关磷脂酶A2 与冠心病的关系

王林林, 陈作元, 张蕊, 田嘉伟, 吕晓冰… - Advances in Clinical …, 2020 - hanspub.org
目的: 研究人血浆脂蛋白相关磷脂酶A2 (Lp-PLA2) 与冠心病的关系. 方法: 选取2018 年11
月至2019 年11 月期间在青岛大学附属医院心血管内科住院的首次疑诊冠心病并行冠状动脉 …

Enhanced cutaneous Rock2 expression as a marker of Rho Kinase pathway activation in autoimmune disease and Kohlemeier-Degos disease

C Magro, Z Schwartz, J Saab, A Hedayat - Annals of Diagnostic Pathology, 2020 - Elsevier
The small guanosine triphosphatase Rho and its target Rho kinase are involved in a
heterogeneous spectrum of cellular activities, many of which are integral to cytoskeletal …

Reactive oxygen species and the regulation of cerebral vascular tone

TM De Silva, FM Faraci - Studies on Atherosclerosis, 2017 - Springer
This chapter summarizes concepts related to the effects of reactive oxygen species and
oxidative stress on vascular tone in the cerebral circulation. The impact of different reactive …

Discovery of vascular Rho kinase (ROCK) inhibitory peptides

R Abbasgholizadeh, H Zhang… - Experimental …, 2019 - journals.sagepub.com
Rho-activated kinases (ROCKs) regulate many cellular functions such as proliferation,
migration, and smooth muscle contractility, but they are also associated with pathogenesis of …

Efecto de la inhibición de RHO kinasa por atorvastatina sobre la polarización de macrófagos infectados con trypanosoma cruzi

FL González Herrera - 2022 - repositorio.uchile.cl
La enfermedad de Chagas (EC) es una enfermedad causada por el protozoo Trypanosoma
cruzi (T. cruzi). La fase crónica de la enfermedad se manifiesta principalmente como …

Exploring the use of high-dose simvastatin as therapy for oxidative stress in disease models of neuroinflammation

CE Bowers - 2021 - discovery.ucl.ac.uk
Background: There is growing evidence that HMG-CoA reductase inhibitors, otherwise
known as the statin family, can exert pleiotropic effects in many areas. Of these, potential …

[PDF][PDF] Vliv polyfenolických látek na vaskulární systém

J Pourová - 2021 - dspace.cuni.cz
Děkuji všem, kteří přispěli k vzniku této habilitační práce. Zejména kolegům z Výzkumné
skupiny kardiovaskulární a respirační farmakologie a toxikologie, prof. Přemyslu …

ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells.

竹田裕介 - International journal of molecular sciences, 2021 - ir.jikei.ac.jp
The small GTPase Rho and its downstream effector, Rho-kinase (ROCK), regulate various
cellular functions, including organization of the actin cytoskeleton, cell adhesion and …