Bioactive inorganic nanomaterials for cancer theranostics

Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Boosting checkpoint immunotherapy with biomaterials

L Liu, Y Pan, C Zhao, P Huang, X Chen, L Rao - ACS nano, 2023 - ACS Publications
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Surface modified lanthanide upconversion nanoparticles for drug delivery, cellular uptake mechanism, and current challenges in NIR-driven therapies

AA Ansari, AK Parchur, G Chen - Coordination chemistry reviews, 2022 - Elsevier
Abstract Lanthanides (Ln 3+) are a particular class of optical materials and are regularly
utilized as a structure block for architectures of optoelectronic frameworks because of their …

Genetically Engineered‐Cell‐Membrane Nanovesicles for Cancer Immunotherapy

Q Cheng, Y Kang, B Yao, J Dong, Y Zhu… - Advanced …, 2023 - Wiley Online Library
The advent of immunotherapy has marked a new era in cancer treatment, offering significant
clinical benefits. Cell membrane as drug delivery materials has played a crucial role in …

[HTML][HTML] Engineered tumor cell-derived vaccines against cancer: The art of combating poison with poison

X Zhang, H Cui, W Zhang, Z Li, J Gao - Bioactive Materials, 2023 - Elsevier
Tumor vaccination is a promising approach for tumor immunotherapy because it presents
high specificity and few side effects. However, tumor vaccines that contain only a single …

A general biomineralization strategy to synthesize autologous cancer vaccines with cGAS-STING activating capacity for postsurgical immunotherapy

Q Li, Z Dong, Z Cao, H Lei, C Wang, Y Hao, L Feng… - ACS …, 2023 - ACS Publications
Autologous cancer vaccines constructed by nonproliferative whole tumor cells or tumor
lysates together with appropriate adjuvants represent a promising strategy to suppress …

Biomimetic and bioinspired nano‐platforms for cancer vaccine development

C Feng, P Tan, G Nie, M Zhu - Exploration, 2023 - Wiley Online Library
The advent of immunotherapy has revolutionized the treating modalities of cancer. Cancer
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …

Tumor Cell Nanovaccines Based on Genetically Engineered Antibody‐Anchored Membrane

Y Li, H Zhang, R Wang, Y Wang, R Li, M Zhu… - Advanced …, 2023 - Wiley Online Library
Despite the promise in whole‐tumor cell vaccines, a key challenge is to overcome the lack of
costimulatory signals. Here, agonistic‐antibody‐boosted tumor cell nanovaccines are …

Lymph node-targeting nanovaccines for cancer immunotherapy

Q Wang, Z Wang, X Sun, Q Jiang, B Sun, Z He… - Journal of Controlled …, 2022 - Elsevier
Cancer immunotherapies such as tumor vaccines, chimeric antigen receptor T cells and
immune checkpoint blockades, have attracted tremendous attention. Among them, tumor …

[HTML][HTML] Multifunctional nanocomposites modulating the tumor microenvironment for enhanced cancer immunotherapy

P Sharma, M Otto - Bioactive Materials, 2024 - Elsevier
Cancer immunotherapy has gained momentum for treating malignant tumors over the past
decade. Checkpoint blockade and chimeric antigen receptor cell therapy (CAR-T) have …