The mouse growth hormone receptor/growth hormone-binding protein (GHR/BP) gene
produces several distinct mRNA forms through alternative splicing, including mRNAs …

The mRNA and the activity of glucose-6-phosphatase (Glc-6-Pase) were present in the liver,
kidney, and small intestine of 15-day-old suckling rats, but were absent from the stomach …

It is difficult to induce the maturation of embryonic stem (ES) cells into hepatocytes in vitro.
We previously reported that Thy1-positive mesenchymal cells derived from the mouse fetal …

Abstract Data from the International Diabetes Federation show that 347 million people
worldwide have diabetes, and the incidence is still rising. Although the treatment of diabetes …

Hepatic gene expression of P-enolpyruvate carboxykinase (PEPCK) and glucose-6-
phosphatase (Glc-6-Pase) is regulated in response to changes in the availability of …

Transcription of the gene encoding the catalytic subunit of glucose-6-phosphatase (G6Pase)
is stimulated by glucocorticoids and strongly repressed by insulin. We have explored the …

Increase dincidences of hepatotoxicity have been observed in diabetic patients receiving
drug therapies. Neither the mechanisms nor the predisposing factors underlying …

Glucose-6-phosphatase catalyzes the terminal step in the gluconeogenic and glycogenolytic
pathways. In HepG2 cells, the maximum repression of basal glucose-6-phosphatase …

We have cloned and sequenced the first 1.2 kb of the 5′ region of the human glucose‐6‐
phosphatase gene. Transfection of H4IIE hepatoma cells with the 1.2 kb fragment fused to a …

Glucose-6-phosphatase (G6Pase) is a key enzyme that is responsible for the production of
glucose in the liver during fasting or in type 2 diabetes mellitus (T2DM). During fasting or in …