Liposomes, noted for their tunable particle size, surface customization, and varied drug
delivery capacities, are increasingly acknowledged in therapeutic applications. These …

During cerebral ischemia-reperfusion conditions, the excessive reactive oxygen species in
the ischemic penumbra region, resulting in neuronal oxidative stress, constitute the main …

The activation of innate immunity following transplantation has been identified as a crucial
factor in allograft inflammation and rejection. However, the role of cyclic guanosine …

Developing strategies to target injured pancreatic acinar cells (PACs) in conjunction with
primary pathophysiology-specific pharmacological therapy presents a challenge in the …

Background Ischemic stroke (IS) occurs when a blood vessel supplying the brain becomes
obstructed, resulting in cerebral ischemia. This type of stroke accounts for approximately …

Vascular recanalization intervention is the primary recommended approach for the treatment
of ischemic stroke. However, the damage caused by cerebral ischemia-reperfusion (I/R) …

Stroke is responsible for 11% of all deaths worldwide, the majority of which are caused by
ischemic strokes, thus making the need to urgently find safe and effective therapies. Today …

In recent years, the frequency of strokes has been on the rise year by year and has become
the second leading cause of death around the world, which is characterized by a high …

Sepsis is a severe systemic inflammatory response commonly occurring in infectious
diseases, caused by infection with virulent pathogens. In the pathogenesis of sepsis, the …

Protein arginine deiminase 4 (PAD4) plays an important role in cancer progression by
participating in gene regulation, protein modification, and neutrophil extracellular trap (NET) …