Canine atopic dermatitis (CAD) has a hereditary basis that is modified by interactions with
the environment, including diet. Differentially expressed genes in non-lesional skin …

X-linked adrenoleukodystrophy (X-ALD) is a neurodegenerative disorder caused by
mutations in the ABCD1 gene, which encodes a peroxisomal member of the ATP-binding …

Hepatic triglyceride (TG) accumulation is considered to be a prerequisite for developing
nonalcoholic fatty liver (NAFL). Peroxisomes have many important functions in lipid …

During pregnancy, fetal glucose production is suppressed, with rapid activation immediately
postpartum. Fatty acid–binding protein 4 (FABP4) was recently demonstrated as a regulator …

In the wake of genomics, metabolomics characterizes the small molecular metabolites
revealing the phenotypes induced by gene mutants. To address the metabolic signatures in …

INTRODUCTION: Vitamin D deficiency has been linked to type 1 and 2 diabetes, whereas
supplementation may prevent both diseases. However, the extent of the effects of vitamin D …

Better understanding of leukodystrophies in neurological routine practice is of crucial
importance for differentiating between other white matter diseases such as toxic …

Physiological dysfunction confers negative valence to coincidental sensory cues to induce
the formation of aversive associative memory. How peripheral tissue stress engages …

Metabolism in trypanosomatids is compartmentalised with major pathways, notably
glycolysis, present in peroxisome-like organelles called glycosomes. To date, little …

X-linked adrenomyeloneuropathy (AMN) is an inherited neurometabolic disorder caused by
malfunction of the ABCD1 gene, characterized by slowly progressing spastic paraplegia …