Human ATP-binding cassette (ABC) transporter ABCD1 transports CoA esters of saturated/
monounsaturated very long chain fatty acid from cytosol to the peroxisome for β-oxidation …

ABSTRACT X-linked adrenoleukodystrophy (X-ALD), the most frequent peroxisomal
disorder, is associated with mutation in the ABCD1 gene which encodes a peroxisomal ATP …

The work I am presenting herein is a mere compilation of what I have contributed to during
the last years. Although the breakthroughs, the highlights have always been the driving force …

Peroxisomes play an essential role in a number of important metabolic pathways including
oxidation of fatty acids, and synthesis of ether phospholipids and bile acids. Long, very long …

X-linked adrenoleukodystrophy (X-ALD) is an inherited neurodegenerative disorder. The
genetic bases for all its different phenotypic variants are mutation in the gene encoding the …

The function of bicarbonate transporters has been extensively studied in epithelial tissues,
but their function in heart is not well understood. Cardiac tissue expresses an abundance of …

One of the major complications of minimal change nephrotic syndrome (MCNS) is
hypercholesterolemia. In non-MCNS experimental rat models of NS, hypercholesterolemia …

Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy_ A
paradigm for axonal degeneration Page 1 Author's Accepted Manuscript Oxidative stress …

The inherited peroxisomal disorder X-linked adrenoleukodystrophy (X-ALD), associated with
neurodegeneration and inflammatory cerebral demyelination, is caused by mutations in the …

Abstract ABCD2 (D2) has been proposed as a peroxisomal long-chain acyl-CoA transporter
that is essential for very long chain fatty acid metabolism. In the livers of mice, D2 is highly …