[HTML][HTML] Heat shock proteins took part in oxidative stress-mediated inflammatory injury via NF-κB pathway in excess manganese-treated chicken livers

Y Liu, M Yu, J Cui, Y Du, X Teng, Z Zhang - … and Environmental Safety, 2021 - Elsevier
Manganese (Mn) is an essential metal in humans and animals. However, excess Mn
entered environment due to the wide application of Mn in industry and agriculture, and …

Th1/Th2 imbalance and heat shock protein mediated inflammatory damage triggered by manganese via activating NF-κB pathway in chicken nervous system in vivo …

Z Miao, K Zhang, R Bao, J Li, Y Tang… - Environmental Science and …, 2021 - Springer
Manganese (Mn) is a ubiquitous heavy metal pollutant in environment, and excess Mn can
damage nervous system of humans and animals. However, molecular mechanism of Mn …

miR-187-5p/apaf-1 axis was involved in oxidative stress-mediated apoptosis caused by ammonia via mitochondrial pathway in chicken livers

Y Xu, Z Li, S Zhang, H Zhang, X Teng - Toxicology and Applied …, 2020 - Elsevier
Abstract Ammonia (NH 3), a toxic gas, is an important cause of atmospheric haze and one of
the main pollutants in air environment of poultry houses, threatening the health of human …

[HTML][HTML] The transcription factor REST up-regulates tyrosine hydroxylase and antiapoptotic genes and protects dopaminergic neurons against manganese toxicity

E Pajarillo, A Rizor, DS Son, M Aschner… - Journal of Biological …, 2020 - ASBMB
Dopaminergic functions are important for various biological activities, and their impairment
leads to neurodegeneration, a hallmark of Parkinson's disease (PD). Chronic manganese …

[HTML][HTML] Association between serum essential metal elements and the risk of schizophrenia in China

J Ma, L Yan, T Guo, S Yang, Y Liu, Q Xie, D Ni… - Scientific Reports, 2020 - nature.com
Numerous essential metal elements (EMEs) are necessary to maintain the proper function of
human body. In this case-control study, we investigated the associations of 11 EMEs …

[HTML][HTML] Exposure to the environmental pollutant ammonia causes changes in gut microbiota and inflammatory markers in fattening pigs

Y Li, R Zhang, X Li, J Li, W Ji, X Zeng, J Bao - … and Environmental Safety, 2021 - Elsevier
Ammonia (NH 3) is a major pollutant in livestock houses and atmospheric environment. It
has been demonstrated that NH 3 can cause a series of damage to animals and human …

Signal Transduction Associated with Mn-induced Neurological Dysfunction

X Zheng, Y Fang, J Lin, J Luo, S Li, M Aschner… - … Trace Element Research, 2023 - Springer
Manganese (Mn) is a heavy metal that occurs widely in nature and has a vital physiological
role in growth and development. However, excessive exposure to Mn can cause …

[HTML][HTML] Manganese-induced apoptosis through the ROS-activated JNK/FOXO3a signaling pathway in CTX cells, a model of rat astrocytes

WH Li, AX Lu, SS Wang, CH Yan - Ecotoxicology and Environmental …, 2023 - Elsevier
Manganese (Mn) is an essential trace element that maintains many normal physiological
functions. However, multi-system disorders would occur once overexposure to Mn …

[HTML][HTML] Effects of acute diquat poisoning on liver mitochondrial apoptosis and autophagy in ducks

J Chen, Y Su, R Lin, F Lin, P Shang… - Frontiers in Veterinary …, 2021 - frontiersin.org
Diquat is an effective herbicide and is widely used in agriculture. Due to persistent and
frequent applications, it enters into nearby aquatic ecosystem and induces toxic effects in …

Pyrroloquinoline quinine and LY294002 changed cell cycle and apoptosis by regulating PI3K-AKT-GSK3β pathway in SH-SY5Y cells

H Ji, J Ma, L Chen, T Chen, S Zhang, J Jia, X Yang… - Neurotoxicity …, 2020 - Springer
To verify the role of PI3K-AKT-GSK3β pathway during manganese (Mn)-induced cell death,
apoptosis, related indicators were investigated. SH-SY5Y cells were directly exposed to …