Inflammatory bowel disease (IBD) is chronic inflammatory disorder of the gastrointestinal
(GI) tract which pose significant social and economic burden on health system. Crohn's …

The genetics of human longevity has long been studied, and in this regard, centenarians
represent a very informative model. Centenarians are characterized by 2 main features: 1) …

Ulcerative colitis (UC), a major type of inflammatory bowel disease, is also a chronic non‑
specific intestinal inflammation condition of unknown etiology. The pathogenesis of UC is …

OBJECTIVE: To study the effect of micro ribonucleic acid (miR)-146a on the development of
ulcerative colitis (UC) and to explore its regulatory effect on the Toll-like receptor 4 …

Background Increasing research indicates that circular RNAs (circRNAs) play critical roles in
the development of ulcerative colitis (UC). This study aimed to determine the role of circRNA …

Background The abnormal differentiation of Th17 cells aggravates ulcerative colitis (UC).
Antimicrobial peptides (AMPs) exert pivotal protection functions against UC. KT2 is a …

MicroRNAs (miRNAs) have emerged as a critical component of regulatory networks that
modulate and fine-tune gene expression in a post-transcriptional manner. The microRNA …

We describe a quantitative detection method for mutated microRNA in human plasma
samples. Specific oligonucleotides designed from a Peyrard-Bishop model allowed accurate …

Gastrointestinal (GI) disorders refer to gastrointestinal tract conditions, ranging from
dyspepsia to inflammatory bowel diseases (IBDs) and malignant tumors. Biomarkers, which …

Objective To investigate the clinical significance of microRNA-146 (miRNA-146) in patients
with ulcerative colitis (UC). Methods The present prospective observational study included …