Pharmacogenomic phase transition from personalized medicine to patient-centric customized delivery

A Radhakrishnan, G Kuppusamy… - The …, 2020 - nature.com
Personalized medicine has been a booming area in clinical research for the past decade, in
which the detailed information about the patient genotype and clinical conditions were …

Thermoresponsive gating membranes embedded with liquid crystal (s) for pulsatile transdermal drug delivery: An overview and perspectives

SY Lin - Journal of controlled release, 2020 - Elsevier
Due to the circadian rhythm regulation of almost every biological process in the human
body, physiological and biochemical conditions vary considerably over the course of a 24-h …

Role of surfactant micellization for enhanced dissolution of poorly water-soluble cilostazol using poloxamer 407-based solid dispersion via the anti-solvent method

G Jin, HV Ngo, JH Cui, J Wang, C Park, BJ Lee - Pharmaceutics, 2021 - mdpi.com
This study aimed to investigate the role of micellization of sodium lauryl sulfate (SLS) in
poloxamer 407 (POX)-based solid dispersions (POX-based SDs) using the anti-solvent …

Investigation of crystallization and salt formation of poorly water-soluble telmisartan for enhanced solubility

C Park, NM Meghani, Y Shin, E Oh, JB Park, JH Cui… - Pharmaceutics, 2019 - mdpi.com
The crystal changes and salt formation of poorly water-soluble telmisartan (TEL) in various
solvents were investigated for enhanced solubility, stability and crystallinity. Polymorphic …

Fatty acid chain length impacts nanonizing capacity of albumin-fatty acid nanomicelles: Enhanced physicochemical property and cellular delivery of poorly water …

C Park, N Meghani, R Loebenberg, JH Cui… - European Journal of …, 2020 - Elsevier
This study aimed to design the ideal nanonizing vehicle for poorly water-soluble model
curcumin (CCM) using fattigation-platform nanotechnology, and to investigate the effects of …

The roles of short and long chain fatty acids on physicochemical properties and improved cancer targeting of albumin-based fattigation-platform nanoparticles …

C Park, N Meghani, H Amin, PHL Tran, TTD Tran… - International journal of …, 2019 - Elsevier
The aim of this study was to investigate the impact of different chain length fatty acids on
physicochemical properties and cancer targeting of fattigation-platform nanoparticles (NPs) …

Shear stress-dependent targeting efficiency using self-assembled gelatin–oleic nanoparticles in a biomimetic microfluidic system

T Kang, C Park, N Meghani, TTD Tran, PHL Tran… - Pharmaceutics, 2020 - mdpi.com
Cellular properties and microenvironments, as well as the characteristics of nanoparticles
(NPs), affect the cellular uptake and cytotoxic effects of drug-loaded NPs. Since there is fluid …

ENHANCED SOLUBILITY OF ANTIHYPERTENSIVE DRUG USING HYDROPHILIC CARRIER-BASED POTENTSOLID DISPERSION SYSTEMS

K Bahmani, Y Singla - International Journal of Pharmacy Research & …, 2019 - ijprt.org
Oral bioavailability enhancement of drug having poor water solubility is considered as a very
hard task in the formulation development of such drugs. The development of solid …

Mesoporous silica nanoparticles accommodating electrospun nanofibers as implantable local drug delivery system processed by cold atmospheric plasma and spin …

N Erdoğan, DŞ Karaman, Ö Yıldız… - Biomedical …, 2024 - iopscience.iop.org
Nanofibers (NF) and nanoparticles are attractive for drug delivery to improve the drug
bioavailability and administration. Easy manipulation of NF as macroscopic bulk material …

[PDF][PDF] Drug delivery via the upper nasal space: A novel route for anesthesiologists, intensivists and emergency department physicians

S Shrewsbury, J Hocevar-Trnka… - J Clin Anesth Intensive …, 2021 - probiologists.com
Many drugs are effective systemically, but slow onset of non-intravenous routes of
administration may limit their clinical utility. While anesthesiologists usually have …