Management of glioblastoma: State of the art and future directions
Glioblastoma is the most common malignant primary brain tumor. Overall, the prognosis for
patients with this disease is poor, with a median survival of< 2 years. There is a slight …
patients with this disease is poor, with a median survival of< 2 years. There is a slight …
[HTML][HTML] Mechanisms of temozolomide resistance in glioblastoma-a comprehensive review
N Singh, A Miner, L Hennis, S Mittal - Cancer drug resistance, 2021 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and has an
exceedingly low median overall survival of only 15 months. Current standard-of-care for …
exceedingly low median overall survival of only 15 months. Current standard-of-care for …
Frontiers in the treatment of glioblastoma: Past, present and emerging
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …
research over the last several decades, the survival rates for GBM have not improved and …
[HTML][HTML] m6A RNA methylation regulates the self-renewal and tumorigenesis of glioblastoma stem cells
RNA modifications play critical roles in important biological processes. However, the
functions of N 6-methyladenosine (m 6 A) mRNA modification in cancer biology and cancer …
functions of N 6-methyladenosine (m 6 A) mRNA modification in cancer biology and cancer …
[HTML][HTML] Glioblastoma: overview of disease and treatment
ME Davis - Clinical journal of oncology nursing, 2016 - ncbi.nlm.nih.gov
Background Glioblastoma (GBM) is the most common and aggressive malignant brain tumor
in adults. Current treatment options at diagnosis are multimodal and include surgical …
in adults. Current treatment options at diagnosis are multimodal and include surgical …
Primary brain and other central nervous system tumors in the United States (2014-2018): A summary of the CBTRUS statistical report for clinicians
Abstract Background The Central Brain Tumor Registry of the United States (CBTRUS)
contains information on all primary brain and other central nervous system (CNS) tumors …
contains information on all primary brain and other central nervous system (CNS) tumors …
[HTML][HTML] N6-methyladenosine links RNA metabolism to cancer progression
Abstract N6-methyladenosine (m6A) is the most abundant mRNA modification. With the
development of antibody-based sequencing technologies and the findings of m6A-related …
development of antibody-based sequencing technologies and the findings of m6A-related …
Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis
Pseudouridine is the most frequent epitranscriptomic modification. However, its cellular
functions remain largely unknown. Here, we show that pseudouridine synthase 7 (PUS7) is …
functions remain largely unknown. Here, we show that pseudouridine synthase 7 (PUS7) is …
[HTML][HTML] Convolutional neural network techniques for brain tumor classification (from 2015 to 2022): Review, challenges, and future perspectives
Y Xie, F Zaccagna, L Rundo, C Testa, R Agati, R Lodi… - Diagnostics, 2022 - mdpi.com
Convolutional neural networks (CNNs) constitute a widely used deep learning approach that
has frequently been applied to the problem of brain tumor diagnosis. Such techniques still …
has frequently been applied to the problem of brain tumor diagnosis. Such techniques still …
[HTML][HTML] Survival outcomes and prognostic factors in glioblastoma
NF Brown, D Ottaviani, J Tazare, J Gregson, N Kitchen… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma is the most common tumour that originates in the brain in
adults. Most of the published data on glioblastoma are from patients in clinical trials who …
adults. Most of the published data on glioblastoma are from patients in clinical trials who …