Increased risky choice during forced abstinence from fentanyl on the cued rat gambling task
KM Hrelja, C Kawkab, DK Avramidis, S Ramaiah… - …, 2024 - Springer
Rationale The use of illicit opioids has arguably never been more risky; street drug potency
can be dangerously high, is often unknown to the consumer, and results in multiple daily …
can be dangerously high, is often unknown to the consumer, and results in multiple daily …
Methamphetamine increases risky choice in rats, but only when magnitude and probability of reinforcement are manipulated within a session
JR Yates, S Adhikari, RE Bako, KL Berling… - Pharmacology …, 2024 - Elsevier
Risky choice is associated with maladaptive behaviors, particularly substance use disorders.
Current animal models of risky choice are often confounded by other constructs like …
Current animal models of risky choice are often confounded by other constructs like …
[HTML][HTML] Effects of systemic oxytocin receptor activation and blockade on risky decision making in female and male rats
The neuropeptide oxytocin is traditionally known for its roles in parturition, lactation, and
social behavior. Other data, however, show that oxytocin can modulate behaviors outside of …
social behavior. Other data, however, show that oxytocin can modulate behaviors outside of …
[HTML][HTML] Neural signatures of opioid-induced risk-taking behavior in the prelimbic prefrontal cortex
CB Quave, AM Vasquez, G Aquino-Miranda, EP Bora… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Opioid use disorder occurs alongside impaired risk-related decision-making, but the
underlying neural correlates are unclear. We developed a novel approach-avoidance …
underlying neural correlates are unclear. We developed a novel approach-avoidance …
Escalation of intravenous fentanyl self-administration and assessment of withdrawal behavior in male and female mice
Y Chen, T Xiao, A Kimbrough - bioRxiv, 2024 - biorxiv.org
Background: The rise in overdose deaths from synthetic opioids, especially fentanyl,
necessitates the development of preclinical models to study fentanyl use disorder (FUD) …
necessitates the development of preclinical models to study fentanyl use disorder (FUD) …
Towards a better understanding of the bidirectional relationship between decision-making and addiction vulnerability
KM Hrelja - 2024 - open.library.ubc.ca
Impaired decision-making is recognized as a diagnostic criterion for many different
psychiatric disorders including gambling disorder and substance use disorders. Habit …
psychiatric disorders including gambling disorder and substance use disorders. Habit …