Nontraumatic lower-extremity amputation is a devastating complication of peripheral artery
disease (PAD) with a high mortality and medical expenditure. There are≈ 150 000 …

Background Statins are guidelines recommended in patients with peripheral artery disease
(PAD) for the prevention of cardiovascular (CV) events. Comprehensive meta-data on the …

Background: The PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitor
evolocumab reduced low-density lipoprotein cholesterol and cardiovascular events in the …

Background Peripheral artery disease (PAD) patients have high morbidity and mortality
rates, demonstrating a need for improved treatment strategies. While underuse and …

High-intensity statins are recommended for patients with peripheral artery disease (PAD).
Critical limb ischemia (CLI) is the most advanced presentation of PAD. The benefit of statins …

Background An increasing number of patients with a peripheral arterial occlusive disease
were put on statins during the past years. This study assessed whether statin therapy was …

Background: Peripheral artery disease (PAD) is associated with increased risk of mortality,
cardiovascular morbidity, and major amputation. Data on major amputation from a large …

Objective Because the treatment of intermittent claudication (IC) is elective, good short-and
long-term outcomes are imperative. The objective of the present study was to examine the …

Peripheral arterial disease (PAD) is a highly prevalent atherosclerotic condition. In patients
with PAD, the presence of intermittent claudication leads to a deterioration in quality of life. In …

Atherosclerosis is a multifactorial, lipoprotein-driven condition that leads to plaque formation
within the arterial tree, leading to subsequent arterial stenosis and thrombosis that accounts …