Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Comparative genomics demonstrated that the chromosomes from bacteria and their viruses
(bacteriophages) are coevolving. This process is most evident for bacterial pathogens where …

Streptococci readily colonize mucosal tissues in the nasopharynx; the respiratory,
gastrointestinal, and genitourinary tracts; and the skin. Each ecological niche presents a …

Neutrophils constitute the dominant cell in the circulation that mediates the earliest innate
immune human responses to infection. The morbidity and mortality from infection rise …

The skin commensal and opportunistic pathogen Staphylococcus epidermidis is the leading
cause of nosocomial and biofilm‐associated infections. Little is known about the …

Biofilms play an important role in many chronic bacterial infections. Production of an
extracellular mixture of sugar polymers called exopolysaccharide is characteristic and …

Polymorphonuclear leukocytes (PMNs, or neutrophils) are critical for human innate immunity
and kill most invading bacteria. However, pathogens such as Staphylococcus aureus avoid …

Prophages were automatically localized in se‐quenced bacterial genomes by a simple
semantic script leading to the identification of 190 prophages in 115 investigated genomes …

The development of bacterial disease has been likened to a'molecular arms race', in which
the host tries to eliminate the bacteria, while the bacteria try to survive in the host. Although …

Many pathogenic bacteria produce extracellular DNase, but the benefit of this enzymatic
activity is not understood. For example, all strains of the human bacterial pathogen group A …