Connexin and pannexin large-pore channels in microcirculation and neurovascular coupling function
Microcirculation homeostasis depends on several channels permeable to ions and/or small
molecules that facilitate the regulation of the vasomotor tone, hyperpermeability, the blood …
molecules that facilitate the regulation of the vasomotor tone, hyperpermeability, the blood …
[HTML][HTML] Connexin 43 expressed in endothelial cells modulates monocyte‑endothelial adhesion by regulating cell adhesion proteins
D Yuan, G Sun, R Zhang, C Luo… - Molecular …, 2015 - spandidos-publications.com
Adhesion between circulating monocytes and vascular endothelial cells is a key initiator of
atherosclerosis. In our previous studies, it was demonstrated that the expression of connexin …
atherosclerosis. In our previous studies, it was demonstrated that the expression of connexin …
Purinergic signaling in nervous system health and disease: Focus on pannexin 1
JC Sanchez-Arias, E van der Slagt… - Pharmacology & …, 2021 - Elsevier
Purinergic signaling encompasses the cycle of adenosine 5′ triphosphate (ATP) release
and its metabolism into nucleotide and nucleoside derivatives, the direct release of …
and its metabolism into nucleotide and nucleoside derivatives, the direct release of …
Charging up the periphery: glial ionic regulation in sensory perception
S Ray, A Singhvi - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
The peripheral nervous system (PNS) receives diverse sensory stimuli from the environment
and transmits this information to the central nervous system (CNS) for subsequent …
and transmits this information to the central nervous system (CNS) for subsequent …
Connexins, gap junctions and peripheral neuropathy
KA Kleopa, I Sargiannidou - Neuroscience letters, 2015 - Elsevier
Gap junctions (GJs) have emerged as an important molecular component of peripheral
myelinated fibers following the discovery of mutations affecting the GJ protein connexin32 …
myelinated fibers following the discovery of mutations affecting the GJ protein connexin32 …
[HTML][HTML] Adenosine triphosphate induced cell death: Mechanisms and implications in cancer biology and therapy
Adenosine triphosphate (ATP) induced cell death (AICD) is a critical cellular process that
has garnered substantial scientific interest for its profound relevance to cancer biology and …
has garnered substantial scientific interest for its profound relevance to cancer biology and …
Connexin 43 hemichannel regulates H9c2 cell proliferation by modulating intracellular ATP and [Ca2+]
D Song, X Liu, R Liu, L Yang, J Zuo… - Acta Biochim Biophys …, 2010 - academic.oup.com
Abstract Connexin 43 (Cx43), known to be the main protein building blocks of gap junctions
and hemichannels in mammalian heart, plays an important role in cardiocytes proliferation …
and hemichannels in mammalian heart, plays an important role in cardiocytes proliferation …
Immunoregulation at the gliovascular unit in the healthy brain: A focus on Connexin 43
AC Boulay, S Cisternino, M Cohen-Salmon - Brain, behavior, and immunity, 2016 - Elsevier
In the brain, immune cell infiltration is normally kept at a very low level and a unique
microenvironment strictly restricts immune reactions and inflammation. Even in such …
microenvironment strictly restricts immune reactions and inflammation. Even in such …
Priming central sound processing circuits through induction of spontaneous activity in the cochlea before hearing onset
CJ Kersbergen, DE Bergles - Trends in neurosciences, 2024 - cell.com
Sensory systems experience a period of intrinsically generated neural activity before
maturation is complete and sensory transduction occurs. Here we review evidence …
maturation is complete and sensory transduction occurs. Here we review evidence …
Low extracellular Ca2+ conditions induce an increase in brain endothelial permeability that involves intercellular Ca2+ waves
M De Bock, M Culot, N Wang, A da Costa, E Decrock… - Brain research, 2012 - Elsevier
The intracellular calcium concentration ([Ca2+] i) is an important factor determining the
permeability of endothelial barriers including the blood–brain barrier (BBB). However …
permeability of endothelial barriers including the blood–brain barrier (BBB). However …