The analysis of neural dynamics in several brain cortices has consistently uncovered low-
dimensional manifolds that capture a significant fraction of neural variability. These neural …

The two basic processes underlying perceptual decisions—how neural responses encode
stimuli, and how they inform behavioral choices—have mainly been studied separately …

The lack of a formal link between neural network structure and its emergent function has
hampered our understanding of how the brain processes information. We have now come …

Sleep exerts many effects on mammalian forebrain networks, including homeostatic effects
on both synaptic strengths and firing rates. We used large-scale recordings to examine the …

Sequences of spiking activity have been heavily implicated as potential substrates of
memory formation and retrieval across many species. A parallel line of recent evidence also …

The brain is organized as a network of highly specialized networks of spiking neurons. To
exploit such a modular architecture for computation, the brain has to be able to regulate the …

Theta oscillations reflect rhythmic inputs that continuously converge to the hippocampus
during exploratory and memory-guided behavior. The theta-nested operations that organize …

The cerebrum is a major center for brain function, and its activity is derived from the
assembly of activated cells in neural networks. It is currently difficult to study complex human …

In the idling brain, neuronal circuits transition between periods of sustained firing (UP state)
and quiescence (DOWN state), a pattern the mechanisms of which remain unclear. Here we …

In the last decade, the involvement of neural oscillatory mechanisms in speech
comprehension has been increasingly investigated. Current evidence suggests that low …