The progress and challenge of anti-PD-1/PD-L1 immunotherapy in treating non-small cell lung cancer

J Qu, Q Mei, L Liu, T Cheng, P Wang… - … in medical oncology, 2021 - journals.sagepub.com
The use of programmed cell-death protein 1 (PD-1)/programmed cell-death ligand 1 (PD-L1)
inhibitors is the standard therapy for the first-line or second-line treatment of patients with …

[HTML][HTML] The association between albumin levels and survival in patients treated with immune checkpoint inhibitors: A systematic review and meta-analysis

DC Guven, TK Sahin, E Erul, A Rizzo… - Frontiers in Molecular …, 2022 - frontiersin.org
Background: The albumin levels may potentially be used as a prognostic biomarker in
patients with cancertreated with immune checkpoint inhibitors (ICIs) due to its close …

[HTML][HTML] The relationship between NLR/PLR/LMR levels and survival prognosis in patients with non-small cell lung carcinoma treated with immune checkpoint …

N Liu, J Mao, P Tao, H Chi, W Jia, C Dong - Medicine, 2022 - journals.lww.com
Background: The relationship between neutrophil to lymphocyte ratio (NLR), platelet to
lymphocyte ratio (PLR), and lymphocyte to monocyte ratio (LMR) and the dire prognosis of …

[HTML][HTML] Inflammatory markers in cancer immunotherapy

D Ravindranathan, VA Master, MA Bilen - Biology, 2021 - mdpi.com
Simple Summary Inflammation has been recognized to be linked to tumor development.
Several markers of inflammation can be detected via blood such as variety of blood cells …

[HTML][HTML] Biomarkers for immune checkpoint inhibitor response in NSCLC: current developments and applicability

K Tostes, AP Siqueira, RM Reis, LF Leal… - International Journal of …, 2023 - mdpi.com
Lung cancer has the highest mortality rate among all cancer types, resulting in over 1.8
million deaths annually. Immunotherapy utilizing immune checkpoint inhibitors (ICIs) has …

[HTML][HTML] Prognostic role of the platelet to lymphocyte ratio (PLR) in the clinical outcomes of patients with advanced lung cancer receiving immunotherapy: A systematic …

K Zhou, J Cao, H Lin, L Liang, Z Shen, L Wang… - Frontiers in …, 2022 - frontiersin.org
Background It remains controversial whether the platelet to lymphocyte ratio (PLR) serves as
a potential indicator for the efficacy of immunotherapy in advanced lung cancer. This meta …

[HTML][HTML] Soluble biomarkers to predict clinical outcomes in non-small cell lung cancer treated by immune checkpoints inhibitors

J Ancel, V Dormoy, BN Raby, V Dalstein… - Frontiers in …, 2023 - frontiersin.org
Lung cancer remains the first cause of cancer-related death despite many therapeutic
innovations, including immune checkpoint inhibitors (ICI). ICI are now well used in daily …

Prognostic value of inflammatory response biomarkers using peripheral blood and [18F]-FDG PET/CT in advanced NSCLC patients treated with first-line chemo-or …

RD Seban, JB Assié, E Giroux-Leprieur, MA Massiani… - Lung Cancer, 2021 - Elsevier
Objectives We aimed to compare the prognostic value of inflammatory biomarkers extracted
from pretreatment peripheral blood and [18F]-FDG PET for estimating outcomes in non-small …

[HTML][HTML] Human leukocyte antigens and biomarkers in type 1 diabetes mellitus induced by immune-checkpoint inhibitors

H Inaba, Y Kaido, S Ito, T Hirobata… - Endocrinology and …, 2022 - synapse.koreamed.org
Background Type 1 diabetes mellitus induced by immune-checkpoint inhibitors (ICI-T1DM)
is a rare critical entity. However, the etiology of ICI-T1DM remains unclear. Methods In order …

[HTML][HTML] Prognostic roles of hematological indicators for the efficacy and prognosis of immune checkpoint inhibitors in patients with advanced tumors: a retrospective …

F Zheng, Q Meng, L Zhang, J Chen, L Zhao… - World Journal of …, 2023 - Springer
Background Immunocheckpoint inhibitor (ICI) is a major breakthrough in tumor treatment. It
can activate the patient's own immune system and play an anti-tumor role, but not all …