Maternal health during pregnancy plays a major role in shaping health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …

The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
during pregnancy on the developing fetal brain is poorly understood. Other antenatal …

Mounting evidence indicates that microglia, which are the resident immune cells of the brain,
play critical roles in a diverse array of neurodevelopmental processes required for proper …

SARS-CoV-2, which causes the Coronavirus Disease 2019 (COVID-19) pandemic, has a
brain neurotropism through binding to the receptor angiotensin-converting enzyme 2 …

Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

The impact of infections and inflammation during pregnancy on the developing fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …

Schizophrenia is a devastating mental illness with a strong genetic component that is the
subject of extensive research. Despite the high heritability, it is well recognized that non …

Autism spectrum disorder (ASD) is a group of complex multifactorial neurodevelopmental
disorders characterized by a wide and variable set of neuropsychiatric symptoms, including …

Human epidemiological studies implicate exposure to infection during gestation in the
etiology of neurodevelopmental disorders. Animal models of maternal immune activation …