Nanoparticle and virus-like particle vaccine approaches against SARS-CoV-2

C Kim, JD Kim, SU Seo - Journal of Microbiology, 2022 - Springer
The global spread of coronavirus disease 2019 caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has provoked an urgent need for …

The P681H mutation in the spike glycoprotein of the alpha variant of SARS-CoV-2 escapes IFITM restriction and is necessary for type I interferon resistance

MJ Lista, H Winstone, HD Wilson, A Dyer… - Journal of …, 2022 - Am Soc Microbiol
The appearance of new dominant variants of concern (VOC) of severe acute respiratory
syndrome coronavirus type 2 (SARS-CoV-2) threatens the global response to the …

T-cell immunity to SARS-CoV-2: what if the known best is not the optimal course for the long run? Adapting to evolving targets

AE Nowill, M Caruso, PO de Campos-Lima - Frontiers in immunology, 2023 - frontiersin.org
Humanity did surprisingly well so far, considering how unprepared it was to respond to the
coronavirus disease 2019 (COVID-19) threat. By blending old and ingenious new …

An efficient and scalable method for the production of immunogenic SARS-CoV-2 virus-like particles (VLP) from a mammalian suspension cell line

S Hirschberg, F Ghazaani, G Ben Amor, M Pydde… - Vaccines, 2023 - mdpi.com
The rapid evolution of new SARS-CoV-2 variants poses a continuing threat to human health.
Vaccination has become the primary therapeutic intervention. The goal of the current work …

A systematic review of virus-like particles of coronavirus: Assembly, generation, chimerism and their application in basic research and in the clinic

W Lu, Z Zhao, YW Huang, B Wang - International Journal of Biological …, 2022 - Elsevier
Virus-like particles (VLPs) are nano-scale particles that are morphologically similar to a live
virus but which lack a genetic component. Since the pandemic spread of COVID-19, much …

Functional severe acute respiratory syndrome coronavirus 2 virus-like particles from insect cells

A Naskalska, A Dabrowska, A Szczepanski… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a major epidemic
threat since the beginning of 2020. Efforts to combat the virus and the associated …

Influenza virus-like particle (VLP) vaccines expressing the SARS-CoV-2 S glycoprotein, S1, or S2 domains

KB Chu, HJ Kang, KW Yoon, HA Lee, EK Moon… - Vaccines, 2021 - mdpi.com
The ongoing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic
had brought disastrous consequences throughout the entire world. While several …

The Application of Biomaterials for the Vaccine, Treatment, and Detection of SARS-CoV-2

Y Hu, L Liu, S Zhang, S Su, X Liang - ACS omega, 2024 - ACS Publications
The coronavirus disease-19 (COVID-19) pandemic has had a significant impact on human
life worldwide since 2019. Specific vaccines and antiviral agents are the most effective …

SARS-CoV-2 virus-like-particles via liposomal reconstitution of spike glycoproteins

S McColman, K Shkalla, P Sidhu, J Liang… - Nanoscale …, 2023 - pubs.rsc.org
The SARS-CoV-2 virus, implicated in the COVID-19 pandemic, recognizes and binds host
cells using its spike glycoprotein through an angiotensin converting enzyme 2 (ACE-2) …

A perspective on SARS-CoV-2 virus-like particles vaccines

X Gao, Y Xia, X Liu, Y Xu, P Lu, J Liu, G Liang - International …, 2023 - Elsevier
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first appeared in
Wuhan, China, in December 2019. The 2019 coronavirus disease (COVID-19) pandemic …