[HTML][HTML] Selenium-containing compounds: a new hope for innovative treatments in Alzheimer's disease and Parkinson's disease
Neurodegenerative diseases are challenging to cure. To date, no cure has been found for
Alzheimer's disease or Parkinson's disease, and current treatments are able only to slow the …
Alzheimer's disease or Parkinson's disease, and current treatments are able only to slow the …
Exploring the antioxidant potential of chalcogen-indolizines throughout in vitro assays
CS Garcia, MJ da Rocha, MH Presa, CS Pires… - PeerJ, 2024 - peerj.com
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are highly reactive
molecules produced naturally by the body and by external factors. When these species are …
molecules produced naturally by the body and by external factors. When these species are …
Role of noradrenergic and dopaminergic systems in the antinociceptive effect of N-(3-(phenylselanyl) prop-2-yn-1-yl) benzamide in mice
KNB Ledebuhr, GDA Nunes, MH Presa… - Toxicology and Applied …, 2024 - Elsevier
Pain has a negative impact on public health, reducing quality of life. Unfortunately, current
treatments are not fully effective and have adverse effects. Therefore, there is a need to …
treatments are not fully effective and have adverse effects. Therefore, there is a need to …
Dopaminergic Modulation and Computational ADMET Insights for the Antidepressant-like Effect of N-(3-(Phenylselanyl)prop-2-yn-1-yl)benzamide
EM Besckow, KNB Ledebuhr, CS Pires… - ACS Chemical …, 2024 - ACS Publications
The compound N-(3-(phenylselanyl) prop-2-yn-1-yl) benzamide (SePB), which combines a
selenium atom and a benzamide nucleus in an organic structure, has demonstrated a fast …
selenium atom and a benzamide nucleus in an organic structure, has demonstrated a fast …
NaOAc-Assisted Aerobic Oxidation Protocol for the Synthesis of Pentacoordinate Chalcogenyl Spirophosphoranes with P–Se/P–S Bonds under Open Air
Y Zhang, Y Guo, Y Zhao, S Cao - The Journal of Organic …, 2024 - ACS Publications
The NaOAc-assisted aerobic oxidation reaction of pentacoordinate
hydrospirophosphoranes and dichalcogenyl compounds with open air as a green oxidant …
hydrospirophosphoranes and dichalcogenyl compounds with open air as a green oxidant …
1-(Phenylselanyl)-2-(p-tolyl) indolizine: A selenoindolizine with potential antidepressant-like activity in mice mediated by the modulation of dopaminergic and …
MJ da Rocha, MH Presa, GDA Nunes, NP Zuge… - Brain Research, 2024 - Elsevier
(Phenylselanyl)-2-(p-tolyl) indolizine (MeSeI) is a selenoindolizine with an antidepressant-
like effect in mice by regulation of the serotonergic system. This study investigated the …
like effect in mice by regulation of the serotonergic system. This study investigated the …
N-(3-((3-(trifluoromethyl) phenyl) selanyl) prop-2-yn-1-yl) benzamide induces antidepressant-like effect in mice: involvement of the serotonergic system
CS Pires, MJ da Rocha, MH Presa, NP Zuge… - …, 2024 - Springer
Objective To evaluate the antidepressant-like effect of N-(3-((3-(trifluoromethyl) phenyl)
selenyl) prop-2-yn-1-yl) benzamide (CF 3 SePB) in mice and the involvement of the …
selenyl) prop-2-yn-1-yl) benzamide (CF 3 SePB) in mice and the involvement of the …
[PDF][PDF] Selenium-containing compounds: a new hope for innovative treatments in Alzheimer's disease and Parkinson's
P Pyka, S Garbo, R Fioravanti, C Jacob, M Hittinger… - researchgate.net
Neurodegenerative diseases are challenging to cure. To date, no cure has been found for
Alzheimer's disease or Parkinson's disease, and current treatments are able only to slow the …
Alzheimer's disease or Parkinson's disease, and current treatments are able only to slow the …
Bis diselenide-based schiff bases as deubiquitination signaling pathway modulators
S Shaaban, A Negm - US Patent 12,006,293, 2024 - Google Patents
US12006293B1 - Bis diselenide-based schiff bases as deubiquitination signaling pathway
modulators - Google Patents US12006293B1 - Bis diselenide-based schiff bases as …
modulators - Google Patents US12006293B1 - Bis diselenide-based schiff bases as …