Obstructive sleep apnea (OSA) is a highly prevalent disorder that has profound implications
on the outcomes of patients with chronic lung disease. The hallmark of OSA is a collapse of …

Background The recent discovery that a combination of noradrenergic and antimuscarinic
drugs improved upper airway muscle function during sleep and reduced OSA severity has …

The health impact of hypercapnic respiratory failure (an increase in arterial blood carbon
dioxide resulting from insufficient alveolar ventilation to match the metabolic production of …

The co-occurrence of COPD and OSA termed the “overlap syndrome”(OVS) was first coined
by Flenley in 1985. 1 Despite being recognized almost 40 years ago, it remains an under …

Commentary on Zheng Y, Yee BJ, Wong K, Grunstein R, Piper A. A pilot randomized trial
comparing CPAP vs bilevel PAP spontaneous mode in the treatment of hypoventilation …

Abstract Study Objectives Symptom impact and neurocognitive function have not been
previously compared between patients with obesity-associated hypoventilation disorders …

The incidence of severe obesity has risen dramatically in the United States and around the
world. A major complication of severe obesity is obesity hypoventilation syndrome (OHS) …

Background Non-invasive ventilation (NIV) is a standard of care for hypercapnic chronic
respiratory failure (CRF). Obstructive sleep apnea syndrome (OSA) frequently contributes to …

Sleep-related breathing disorders (SRBD) comprise obstructive sleep apnea (OSA), central
sleep apnea (CSA), obesity-hypoventilation syndrome (OHS), as well as isolated sleep …

The presence of obstructive sleep apnea (OSA) in patients with chronic obstructive
pulmonary disease (COPD) is referred to as the overlap syndrome. These individuals are at …