Epigenetics and the environmental regulation of the genome and its function
There are numerous examples in psychology and other disciplines of the enduring effects of
early experience on neural function. In this article, we review the emerging evidence for …
early experience on neural function. In this article, we review the emerging evidence for …
Epigenetic regulation of gene expression in physiological and pathological brain processes
Over the past decade, it has become increasingly obvious that epigenetic mechanisms are
an integral part of a multitude of brain functions that range from the development of the …
an integral part of a multitude of brain functions that range from the development of the …
Brain-derived neurotrophic factor: a dynamic gatekeeper of neural plasticity
KK Cowansage, JE LeDoux… - Current molecular …, 2010 - ingentaconnect.com
Brain derived neurotrophic factor (BDNF), a member of the neurotrophin family of structurally
related proteins that promote neuronal differentiation and survival during development [1, 2] …
related proteins that promote neuronal differentiation and survival during development [1, 2] …
Epigenetic regulation of the BDNF gene: implications for psychiatric disorders
F Boulle, DLA Van Den Hove, SB Jakob… - Molecular …, 2012 - nature.com
Abnormal brain-derived neurotrophic factor (BDNF) signaling seems to have a central role in
the course and development of various neurological and psychiatric disorders. In addition …
the course and development of various neurological and psychiatric disorders. In addition …
The potential of HDAC inhibitors as cognitive enhancers
Histone acetylation is a prominent epigenetic modification of the central nervous system that
is unequivocally associated with an increase in the rate of gene transcription. Because gene …
is unequivocally associated with an increase in the rate of gene transcription. Because gene …
Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder
Epigenetic alterations of the brain-derived neurotrophic factor (Bdnf) gene have been linked
with memory, stress, and neuropsychiatric disorders. Here we examined whether there was …
with memory, stress, and neuropsychiatric disorders. Here we examined whether there was …
Fear extinction and BDNF: translating animal models of PTSD to the clinic
R Andero, KJ Ressler - Genes, Brain and Behavior, 2012 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is the most studied neurotrophin involved in
synaptic plasticity processes that are required for long‐term learning and memory …
synaptic plasticity processes that are required for long‐term learning and memory …
How the epigenome integrates information and reshapes the synapse
RR Campbell, MA Wood - Nature Reviews Neuroscience, 2019 - nature.com
In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …
encodes information to form long-lasting memories that lead to stable changes in behaviour …
The epigenetics of social adversity in early life: implications for mental health outcomes
PO McGowan, M Szyf - Neurobiology of disease, 2010 - Elsevier
An organism's behavioral and physiological and social milieu influence and are influenced
by the epigenome, which is composed predominantly of chromatin and the covalent …
by the epigenome, which is composed predominantly of chromatin and the covalent …
Stress and trauma: BDNF control of dendritic-spine formation and regression
MR Bennett, J Lagopoulos - Progress in neurobiology, 2014 - Elsevier
Chronic restraint stress leads to increases in brain derived neurotrophic factor (BDNF)
mRNA and protein in some regions of the brain, eg the basal lateral amygdala (BLA) but …
mRNA and protein in some regions of the brain, eg the basal lateral amygdala (BLA) but …