Advances in the development of therapeutics for cytomegalovirus infections

E Acosta, T Bowlin, J Brooks, L Chiang… - The Journal of …, 2020 - academic.oup.com
The development of therapeutics for cytomegalovirus (CMV) infections, while progressing,
has not matched the pace of new treatments of human immunodeficiency virus (HIV) …

Role of epigenetic modification in interferon treatment of hepatitis B virus infection

Z Yang, B Sun, J Xiang, H Wu, S Kan, M Hao… - Frontiers in …, 2022 - frontiersin.org
Human hepatitis B virus (HBV) is a small, enveloped DNA virus that causes acute and
chronic hepatitis. Chronic hepatitis B (CHB) is associated with hepatocellular carcinoma …

The functional and antiviral activity of interferon alpha-inducible IFI6 against hepatitis B virus replication and gene expression

M Sajid, H Ullah, K Yan, M He, J Feng… - Frontiers in …, 2021 - frontiersin.org
Hepatitis B virus is an enveloped DNA virus, that infects more than three hundred and sixty
million people worldwide and leads to severe chronic liver diseases. Interferon-alpha …

[PDF][PDF] Type-I-IFN-stimulated gene TRIM5γ inhibits HBV replication by promoting HBx degradation

G Tan, Z Yi, H Song, F Xu, F Li, R Aliyari, H Zhang… - Cell reports, 2019 - cell.com
To understand the molecular mechanisms that mediate the anti-hepatitis B virus (HBV) effect
of interferon (IFN) therapy, we conduct high-throughput bimolecular fluorescence …

Antiviral therapy in hepatitis B virus-infected children with immune-tolerant characteristics: A pilot open-label randomized study

S Zhu, H Zhang, Y Dong, L Wang, Z Xu, W Liu… - Journal of …, 2018 - Elsevier
Background & Aim Chronic infection with hepatitis B virus (HBV) in children is a serious
health problem worldwide. How to treat children with immune-tolerant chronic hepatitis B …

Can G-quadruplex become a promising target in HBV therapy?

Y Teng, M Zhu, Y Chi, L Li, Y Jin - Frontiers in Immunology, 2022 - frontiersin.org
The chronic infection with hepatitis B virus (HBV) is an important health problem that affects
millions of people worldwide. Current therapies for HBV always suffer from a poor response …

Interferon response in hepatitis C virus-infected hepatocytes: issues to consider in the era of direct-acting antivirals

PS Sung, EC Shin - International journal of molecular sciences, 2020 - mdpi.com
When interferons (IFNs) bind to their receptors, they upregulate numerous IFN-stimulated
genes (ISGs) with antiviral and immune regulatory activities. Hepatitis C virus (HCV) is a …

Advancing immune and cell-based therapies through imaging

V Ponomarev - Molecular Imaging and Biology, 2017 - Springer
Immunotherapies include various approaches, ranging from stimulating effector
mechanisms to counteracting inhibitory and suppressive mechanisms, and creating a forum …

Ribavirin and its analogs: Сan you teach an old dog new tricks?

MV Chudinov - Fine Chemical Technologies, 2019 - finechem-mirea.ru
Аннотация Обзор посвящен современному состоянию синтетических и биологических
исследований аналогов рибавирина. Рибавирин–нуклеозидный противовирусный …

[PDF][PDF] Рибавирин и его аналоги: можно ли старую собаку научить новым фокусам?

МВ Чудинов - Тонкие химические технологии.-2019.-14 (4).-С, 2019 - researchgate.net
Обзор посвящен современному состоянию синтетических и биологических
исследований аналогов рибавирина. Рибавирин–нуклеозидный противовирусный …