Viral oncology: molecular biology and pathogenesis

UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

A review of new findings in adult T-cell leukemia–lymphoma: A focus on current and emerging treatment strategies

O Hermine, JC Ramos, K Tobinai - Advances in therapy, 2018 - Springer
Adult T-cell leukemia–lymphoma (ATL), a rare and aggressive T-cell malignancy caused by
human T-cell lymphotropic virus type 1 (HTLV-1), is associated with a poor prognosis …

Polycomb-dependent epigenetic landscape in adult T-cell leukemia

D Fujikawa, S Nakagawa, M Hori… - Blood, The Journal …, 2016 - ashpublications.org
Adult T-cell leukemia-lymphoma (ATL) shows global gene expression alterations that confer
cellular characteristics and unfavorable prognosis. However, molecular mechanisms of the …

Ethanolic extract of Nymphaea lotus L. (Nymphaeaceae) leaves exhibits in vitro antioxidant, in vivo anti-inflammatory and cytotoxic activities on Jurkat and MCF-7 …

BB N'guessan, AD Asiamah, NK Arthur… - … medicine and therapies, 2021 - Springer
Abstract Background Nymphaea lotus L.(N. lotus) is an aquatic plant with anecdotal reports
suggesting its use in the traditional management of cancer. However, there is a paucity of …

Thymoquinone enhances the anticancer activity of doxorubicin against adult T-cell leukemia in vitro and in vivo through ROS-dependent mechanisms

M Fatfat, I Fakhoury, Z Habli, R Mismar… - Life sciences, 2019 - Elsevier
Aims Adult T-cell leukemia (ATL) is a mature T-cell neoplasm associated with human T-cell
lymphotropic virus (HTLV-1) infection. Major limitations in Doxorubicin (Dox) chemotherapy …

Constitutive activation of Pim1 kinase is a therapeutic target for adult T-cell leukemia

M Bellon, L Lu, C Nicot - Blood, The Journal of the American …, 2016 - ashpublications.org
Constitutive activation of Pim1 kinase is a therapeutic target for adult T-cell leukemia | Blood |
American Society of Hematology Skip to Main Content Advertisement Umbrella Alt Text …

T-cell lymphomas, a challenging disease: types, treatments, and future

H Ma, M Abdul-Hay - International journal of clinical oncology, 2017 - Springer
T-cell lymphomas are rare and aggressive malignancies associated with poor outcome,
often because of the development of resistance in the lymphoma against chemotherapy as …

Functional comparison of HBZ and the related APH-2 protein provides insight into human T-cell leukemia virus type 1 pathogenesis

AR Panfil, NJ Dissinger, CM Howard… - Journal of …, 2016 - Am Soc Microbiol
MATERIALS AND METHODS Cell lines and culture. HEK293T and HepG2 cells were
maintained in Dulbecco's modified Eagle's medium (DMEM) supplemented with 10% fetal …

Infection with human retroviruses other than HIV-1: HIV-2, HTLV-1, HTLV-2, HTLV-3 and HTLV-4

D Nicolás, J Ambrosioni, R Paredes… - Expert review of anti …, 2015 - Taylor & Francis
HIV-1 is the most prevalent retrovirus, with over 30 million people infected worldwide.
Nevertheless, infection caused by other human retroviruses like HIV-2, HTLV-1, HTLV-2 …

WRN-targeted therapy using inhibitors NSC 19630 and NSC 617145 induce apoptosis in HTLV-1-transformed adult T-cell leukemia cells

R Moles, XT Bai, H Chaib-Mezrag, C Nicot - Journal of Hematology & …, 2016 - Springer
Background Human T-cell leukemia virus type 1 (HTLV-1) infection is associated with adult
T-cell leukemia/lymphoma (ATLL), a lymphoproliferative malignancy with a dismal prognosis …