Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

In mammalian species an optimal fertilization window during which successful fertilization
occurs. In the majority of mammals estrus marks ovulation time and coincident with mating …

Meiotic maturation and cumulus expansion are essential for the generation of a
developmentally competent gamete, and both processes can be recapitulated in vitro. We …

Research aimed at preserving female fertility is increasingly using bioengineering
techniques to develop new platforms capable of supporting ovarian cell function in vitro and …

Comprehensively understanding the female reproductive system is crucial for safeguarding
fertility and preventing diseases concerning women's health. With the capacity to simulate …

The leading indicator for successful outcomes in in-vitro fertilization (IVF) is the quality of
gametes in oocytes and sperm. Thus, advanced research aims to highlight the parameter in …

In the field of assisted reproductive technologies, oocyte in vitro maturation (IVM) has
emerged as a potential alternative to overcome the limitations associated with standard …

Postovulatory aging oocytes usually feature diminished potential for fertilization and poor
embryonic development due to enhanced oxidative damage to the subcellular organelles …

Background The gene expression of anti-Mullerian hormone receptor type 2 (AMHR2) and
follicle stimulating hormone receptor (FSHR) in cumulus cells (CCs) isolated from mature …

An age-dependent increase in ribosomal DNA (rDNA) methylation has been observed
across a broad spectrum of somatic tissues and the male mammalian germline. Bisulfite …