Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …
Effects of dietary fibre on metabolic health and obesity
Obesity and metabolic syndrome represent a growing epidemic worldwide. Body weight is
regulated through complex interactions between hormonal, neural and metabolic pathways …
regulated through complex interactions between hormonal, neural and metabolic pathways …
The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis
Z Jin, Y Yang, Y Cao, Q Wen, Y Xi, J Cheng, Q Zhao… - Microbiome, 2023 - Springer
Background Aging-related fertility decline is a prevalent concern globally. Male reproductive
system aging is mainly characterized by a decrease in sperm quality and fertility. While it is …
system aging is mainly characterized by a decrease in sperm quality and fertility. While it is …
Water extract of goji berries improves neuroinflammation induced by a high-fat and high-fructose diet based on the bile acid-mediated gut–brain axis pathway
W Dong, Y Huang, Y Shu, X Fan, X Tian, Y Yan, J Mi… - Food & Function, 2023 - pubs.rsc.org
The high-fat and high-fructose diet (HFFD) is a common diet in westernized societies, which
worsens disturbances in gut microbiota and bile acid (BA) metabolism. Herein, the present …
worsens disturbances in gut microbiota and bile acid (BA) metabolism. Herein, the present …
High fat diet and high sucrose intake divergently induce dysregulation of glucose homeostasis through distinct gut microbiota-derived bile acid metabolism in mice
X He, X Gao, Y Hong, J Zhong, Y Li… - Journal of Agricultural …, 2023 - ACS Publications
A high calorie diet such as excessive fat and sucrose intake is always accompanied by
impaired glucose homeostasis such as T2DM (type 2 diabetes mellitus). However, it remains …
impaired glucose homeostasis such as T2DM (type 2 diabetes mellitus). However, it remains …
Interactions between dietary cholesterol and intestinal flora and their effects on host health
Y Liu, H Xiao, Z Wang, Q Pan, X Zhao… - Critical Reviews in Food …, 2023 - Taylor & Francis
The interactions between dietary cholesterol and intestinal microbiota strongly affect host
health. In recent years, relevant studies have greatly advanced this field and need to be …
health. In recent years, relevant studies have greatly advanced this field and need to be …
The gut microbiota and diabetes: research, translation, and clinical applications – 2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum
M Byndloss, S Devkota, F Duca, JH Niess… - Diabetologia, 2024 - Springer
This article summarises the state of the science on the role of the gut microbiota (GM) in
diabetes from a recent international expert forum organised by Diabetes, Diabetes Care …
diabetes from a recent international expert forum organised by Diabetes, Diabetes Care …
Bile acids in autoimmune liver disease: unveiling the nexus of inflammation, inflammatory cells, and treatment strategies
T Zhou, AG Ismail, H Francis - Cells, 2023 - mdpi.com
As bile acids not solely play an essential role in nutrition absorption, but also in regulating
metabolic functions as well as immune response, bile acids and their signaling pathways …
metabolic functions as well as immune response, bile acids and their signaling pathways …
Gut microbiota-derived 12-ketolithocholic acid suppresses the IL-17A secretion from colonic group 3 innate lymphoid cells to prevent the acute exacerbation of …
N Li, P Ma, Y Li, X Shang, X Nan, L Shi, X Han, J Liu… - Gut …, 2023 - Taylor & Francis
Intestinal microbiota dysbiosis and metabolic disruption are well-known as the primary
triggers of ulcerative colitis (UC). However, their role in regulating the group 3 innate …
triggers of ulcerative colitis (UC). However, their role in regulating the group 3 innate …
Association of gastrointestinal microbiome and obesity with gestational diabetes mellitus-an updated globally based review of the high-quality literatures
J Li, M Wang, S Ma, Z Jin, H Yin, S Yang - Nutrition & Diabetes, 2024 - nature.com
Objectives The purpose of this review is to investigate the relationship between
gastrointestinal microbiome, obesity, and gestational diabetes mellitus (GDM) in an …
gastrointestinal microbiome, obesity, and gestational diabetes mellitus (GDM) in an …