Importance Mortality among people with opioid dependence is higher than that of the
general population. Opioid agonist treatment (OAT) is an effective treatment for opioid …

Importance More than 42 000 Americans died of opioid overdoses in 2016, and the fatalities
continue to increase. This review analyzes the factors that triggered the opioid crisis and its …

The US mortality rate has gone up three years in a row from 2014 to 2017 (Xu, Murphy,
Kochanek, & Arias, 2016; Murphy, Xu, Kochanek, & Arias, 2018; Kochanek, Murphy, Xu, & …

Stigma as a fundamental hindrance to the United States opioid overdose crisis response |
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Increases in Drug and Opioid Overdose Deaths—United States, 2000–2014 - ScienceDirect
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This paper documents a marked increase in the all-cause mortality of middle-aged white
non-Hispanic men and women in the United States between 1999 and 2013. This change …

Relationship between Nonmedical Prescription-Opioid Use and Heroin Use | NEJM Skip to
main content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare …

ABSTRACT On March 26, 2015, the Office of the Assistant Secretary for Planning and
Evaluation of the US Department of Health and Human Services (HSS) published an online …

While much of the social and political attention surrounding the nationwide opioid epidemic
has focused on the dramatic increase in overdose deaths among white, middle-class …

Oxidative stress (OS), defined as an overabundance of reactive oxygen species (ROS) or a
deficiency of antioxidants, has been linked to sperm damage and male infertility. There are …