Immunology and immunotherapy of cholangiocarcinoma
Cholangiocarcinoma is the second most common primary liver cancer. Its incidence is low in
the Western world but is rising globally. Surgery, chemotherapy and radiation therapy have …
the Western world but is rising globally. Surgery, chemotherapy and radiation therapy have …
[HTML][HTML] The role of tumor-infiltrating lymphocytes in cholangiocarcinoma
Cholangiocarcinoma (CCA) is the second most common primary liver cancer and
associated with a dismal prognosis due to the lack of an efficient systemic therapy. In …
associated with a dismal prognosis due to the lack of an efficient systemic therapy. In …
[HTML][HTML] Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single …
GM Shi, XY Huang, D Wu, HC Sun, F Liang… - Signal transduction and …, 2023 - nature.com
Advanced intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis. Here, we report
the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin …
the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin …
[HTML][HTML] Lacking immunotherapy biomarkers for biliary tract cancer: a comprehensive systematic literature review and meta-analysis
Background: Immunotherapy has recently been incorporated into the spectrum of biliary tract
cancer (BTC) treatment. The identification of predictive response biomarkers is essential in …
cancer (BTC) treatment. The identification of predictive response biomarkers is essential in …
[HTML][HTML] Immune microenvironment of cholangiocarcinoma: Biological concepts and treatment strategies
X Yu, L Zhu, T Wang, J Chen - Frontiers in Immunology, 2023 - frontiersin.org
Cholangiocarcinoma is characterized by a poor prognosis with limited treatment and
management options. Chemotherapy using gemcitabine with cisplatin is the only available …
management options. Chemotherapy using gemcitabine with cisplatin is the only available …
[HTML][HTML] Neoadjuvant and adjuvant therapy in intrahepatic cholangiocarcinoma
X Chen, J Du, J Huang, Y Zeng… - Journal of Clinical and …, 2022 - ncbi.nlm.nih.gov
Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer and
causes major economic and health burdens throughout the world. Although the incidence of …
causes major economic and health burdens throughout the world. Although the incidence of …
Tumor immune microenvironment and the current immunotherapy of cholangiocarcinoma
S Yang, R Zou, Y Dai, Y Hu, F Li… - … Journal of Oncology, 2023 - spandidos-publications.com
Cholangiocarcinoma (CCA) is a highly heterogeneous malignancy originating from the
epithelial system of the bile ducts, and its incidence in recent years is steadily increasing …
epithelial system of the bile ducts, and its incidence in recent years is steadily increasing …
[HTML][HTML] Autoimmune pancreatitis and pancreatic cancer: Epidemiological aspects and immunological considerations
D Poddighe - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
Ordinary chronic pancreatitis is a well-known risk factor for pancreatic cancer, whereas such
an association with autoimmune pancreatitis (AIP) is widely debated. Due to the rarity of the …
an association with autoimmune pancreatitis (AIP) is widely debated. Due to the rarity of the …
[HTML][HTML] Targeting tumor microenvironment for cholangiocarcinoma: Opportunities for precision medicine
R Carloni, A Rizzo, AD Ricci, A Di Federico… - Translational …, 2022 - Elsevier
Systemic treatments (eg, chemotherapy and targeted therapies) have limited efficacy for
patients with locally advanced–unresectable–and metastatic cholangiocarcinoma (CCA) …
patients with locally advanced–unresectable–and metastatic cholangiocarcinoma (CCA) …
PD-L1 expression on immune cells, but not on tumor cells, is a favorable prognostic factor for patients with intrahepatic cholangiocarcinoma
Cholangiocarcinoma, the second most common liver malignancy, after hepatocarcinoma is
highly aggressive and usually diagnosed in advanced cases. In the era of personalized …
highly aggressive and usually diagnosed in advanced cases. In the era of personalized …