Iron is a critical metal for several vital biological processes. Most of the body's iron is bound
to hemoglobin in erythrocytes. Iron from senescent red blood cells is recycled by …

Significant research and preclinical investment in cancer nanomedicine has produced
several products, which have improved cancer care. Nevertheless, there exists a perception …

Axicabtagene ciloleucel (axi-cel) is a chimeric antigen receptor (CAR) T-cell therapy for
relapsed or refractory large B-cell lymphoma (LBCL). This study evaluated whether immune …

This review delves into the intricate relationship between anemia, iron metabolism, and
human immunodeficiency virus (HIV), aiming to unravel the interconnected pathways that …

Immunometabolism explores how the intracellular metabolic pathways in immune cells can
regulate their function under different micro-environmental and (patho-)-physiological …

Iron is an essential element for numerous fundamental biologic processes, but excess iron is
toxic. Abnormalities in systemic iron balance are common in patients with chronic kidney …

Infections in the first year of life are common and often severe. The newborn host
demonstrates both quantitative and qualitative differences to the adult in nearly all aspects of …

Iron is an essential trace element for multicellular organisms and nearly all microorganisms.
Although iron is abundant in the environment, common forms of iron are minimally soluble …

Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

Thirty years after the discovery of its production by activated macrophages, our appreciation
of the diverse roles of nitric oxide (NO) continues to grow. Recent findings have not only …